How a breakthrough new fertility test is offering hope for families who have suffered miscarriages

The test looks at the DNA of the mother to find the optimal time to conceive.

December 14, 2018, 8:34 AM

A Chicago couple who previously suffered two miscarriages recently welcomed a healthy baby boy thanks to a breakthrough new fertility test which helps women struggling with achieving a successful pregnancy by examining the mother's DNA.

The test is offering new hope to many family's struggling to conceive.

Carolyn Bilson and Tim O'Brien met three years ago, and say it was love at first sight.

"Literally a month later we knew, we wanted to have children," Bilson told "Good Morning America."

Carolyn Bilson and Tim O'Brien used the Endometrial Receptivity Test to help them conceive.
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But after two miscarriages, Bilson, then pushing 40, said the couple sought help from a fertility specialist in Chicago who recommended in vitro fertilization.

Their first attempt at IVF, however, failed too, according to Bilson.

"I think it was just so devastating, because we didn't anticipate that," she said. "We thought the hard part would be getting pregnant, not staying pregnant."

O'Brien added that the most "frustrating thing" was that "you didn't learn anything from the previous miscarriage. So, there wasn't, 'What could we do differently?'"

The couple then learned about a new way to tailor fertility treatments specifically to the DNA of the mother, using a test that can help couples figure out the perfect time for conception, based on that DNA.

VIDEO: How a breakthrough new fertility test offers hope for families struggling to conceive
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The Endometrial Receptivity Test uses a tissue sample to look at 238 genes to find out the optimum time for conception, thus increasing the couple's chance to conceive.

For Bilson, that time is two days later than the average woman.

Dr. Ilan Tur-Kaspa, an OB-GYN and the director of Chicago's Institute for Human Reproduction, described the process as "personalized medicine."

Carolyn Bilson and Tim O'Brien meet with Dr. Ilan Tur-Kaspa, an OB-GYN and the director of Chicago's Institute for Human Reproduction.
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"This is what we are trying to do here by personalized medicine," Tur-Kaspa said, adding that you can "make sure" that "the uterus is ready, and optimize a time for implantation."

The result: Their beautiful baby Westley, who is now nine months old.

"We're so lucky," Bilson said. "We're so blessed."

Carolyn Bilson holds her son, Westley.
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OB-GYN Dr. Jessica Shepherd told "GMA" that this breakthrough new treatment is very exciting to the medical community because it offers another avenue for women who have recurrent miscarriages to potentially get pregnant, when it is something they never thought they could look forward to.

The new technique works by having a doctor take a sample of the women's endometrial tissue, which you can get DNA from, and from that DNA you can tell what part of the cycle is prime time to take the fertilized egg and implant it via IVF, Shepherd added.

Shepherd said that the ideal candidates are women who have had three or more miscarriages or women over 40, but emphasized that the test is not for everyone and infertility is a spectrum.

One risk of the procedure many women may not take into account is the emotional effects of it not working and you still miscarrying, Shepherd said. It is a new process and important to go over the risks of the procedure -- which can vary per person -- with your health care provider.