For it's 16th annual Hollywood issue, Vanity Fair spotlights the young female ingénue.
This year's cover, photographed once again by Annie Leibovitz, includes nine of Hollywood's hot young actresses from Abbie Cornish to Evan Rachel Wood.
Abbie Cornish, 27, had her American breakthrough with fellow Australian Heath Ledger as a junkie in 2006's "Candy" but may have been at her loveliest in Jane Campion's "Bright Star," as Fanny Brawne, John Keats's flirty and forthright muse.
You might also know Cornish as the young woman who would become Ryan Phillippe's girlfriend after his split from Reese Witherspoon. The pair played opposite one another in the Iraq war drama "Stop-Loss."
After her pitch-perfect portrayal of an indignant, tightly wound American in Woody Allen's "Vicky Cristina Barcelona," Rebecca Hall, 27, brought her charm and wit to the role of David Frost's delightfully fabulous girlfriend in "Frost/Nixon."
Next up is Nicole Holofcener's "Please Give," and Ben Affleck's Boston crime drama "The Town."
Anna Kendrick, 24, has already shown impressive range, from Bella Swan's twit friend Jessica in the "Twilight" saga to George Clooney's buttoned-up colleague in "Up in the Air," for which she received an Oscar nomination Tuesday.
She was also nominated for a Tony at age 12 for her role in the 1998 Broadway musical "High Society" and is set to star with Michael Cera and Jason Schwartzman in "Scott Pilgram vs. the World."
Four years after her first movie role as Keira Knightley's giddy sister in "Pride and Prejudice," Carey Mulligan, 24, was the buzz of Sundance, thanks to her Oscar-nominated performance as a 1960s English high school senior in "An Education."
Mark Romanek chose her as the lead in "Never Let Me Go," while Oliver Stone cast her in "Wall Street 2: Money Never Sleeps," as the daughter of Gordon Gekko, and Shia LaBeouf's love interest. Seems she's his love interest in real life too.
Since her starring role in the movie musical "Mamma Mia!," Amanda Seyfried, 24, has become the go-to girl for modern-day fairy tales, including Lasse Hallström's "Dear John," and the forthcoming "Letters to Juliet."
Watch for a complete 180, though, in "Chloe," an arty sexual thriller out this month.
Kristen Stewart, 19, brought a twitchy angst to her role as Bella Swan in the "Twilight" series that proved her to be a tough-minded, no-frills anomaly in Hollywood.
Between "Twilight" installments, her edgy trajectory continues with "Welcome to the Rileys," about the friendship between a stripper and a married businessman, played by James Gandolfini, and "The Runaways," about rocker Joan Jett.
Emma Stone, 21, moved to Hollywood with her mother at 15 after giving her parents a PowerPoint presentation about ditching high school for a career in acting.
She held her own with the boys of "Superbad," opposite Jonah Hill, and struck gold last year with her role in "Zombieland."
Mia Wasikowska, 20, had her breakthrough as the fragile yet fierce gymnast Sophie on HBO's "In Treatment."
Edward Zwick cast her in 2009's "Defiance," about a group of Polish Jews banding together to escape the Nazis. Upcoming roles include everything from the lead in Tim Burton's "Alice in Wonderland" to a turn as the love interest in Gus Van Sant's next film.
Evan Rachel Wood
Evan Rachel Wood, 24, mesmerized audiences in Catherine Hardewicke's "Thirteen," a tour de force of teenage angst, but it was her role in Darren Aronofsky's "The Wrestler," as Mickey Rourke's estranged daughter, that distinguished her.
She continues on her trail of off-the-beaten-path roles with "Spider-Man," the upcoming Broadway musical.
The March Hollywood Issue of Vanity Fair hits newsstands today in New York and Los Angeles and nationally Feb. 9.
ABC News' Luchina Fisher contributed to this article.