New Treatments to Help You Quit Smoking

Oct. 21, 2008— -- Some people can smoke for years and give up the habit without any problem, but most smokers are not so lucky. After a few days, without warning, they light up another cigarette.

"It is an overpowering feeling that you must have a cigarette right now," said Monica Collins, a smoker, who's now on her fourth attempt to quit. 

The nicotine in cigarettes can be that addictive, and current quit-smoking treatments are usually not enough.   

"You cannot resist the craving," said Julie Gelfand, who's smoked a pack a day for 10 years and has tried repeatedly to stop. "You cannot keep fighting." 

Studies show that 90 percent of smokers trying to quit will relapse within the first year, according to the Massachusetts General Hospital in Boston. Most smokers try to quit and fail several times before they succeed. But new cutting-edge products are being developed that may help more smokers finally kick the habit.  

Perhaps the most revolutionary approach is a nicotine vaccine. Several versions are undergoing clinical trials.  The vaccine is given to smokers in a series of four or five shots over several months. 

Normally when someone smokes, nicotine molecules enter the bloodstream, and travel up into the brain to produce pleasure. The vaccine prompts the body's immune system to produce antibodies that latch on to the nicotine particles, making them so big they can no longer enter the brain.

"So you're essentially starving the brain of nicotine," explained Dr. Nancy Rigotti, director of the Tobacco Research and Treatment Center at Mass General. "So when somebody smokes, they don't get any satisfaction.  They don't get the reward from smoking so after a while they stop." 

If a vaccine proves safe and effective in larger studies, one could be available within a few years.