While Russia launched massive missile strikes across Ukraine overnight, Ukrainian forces have claimed to have attacked a Russian military base on the occupied Crimean Peninsula.

A source in Ukraine's security services told ABC News on Thursday that Ukrainian forces had hit the Saki airfield in Moscow-annexed Crimea, using an initial wave of drones to "overload" Russian air defense. Russian air force assets were then struck using Neptune missiles designed and produced by Ukraine, according to the source.

Multiple unverified videos of the Ukrainian attack were circulating online Thursday.

-ABC News' Yulia Drozd, Oleksiy Pshemyskiy, Tatyana Rymarenko and Tom Soufi-Burridge

Russian forces launched missile strikes on at least five Ukrainian cities late Wednesday and early Thursday, just hours before Ukrainian President Volodymyr Zelenskyy's planned meeting with U.S. President Joe Biden in Washington, D.C.

Ukrainian Foreign Minister Dmytro Kuleba, who is traveling with Zelenskyy in the United States, described the strikes as "a massive missile attack" on civilian infrastructure, while Ukrainian state-owned grid operator Ukrenergo said it's the first major attack on the country's energy infrastructure in six months.

Russian forces fired a total of 43 missiles across Ukraine from east to west, and 36 of them were shot down by Ukrainian air defense, according to Gen. Valeriy Zaluzhny, commander-in-chief of the Ukrainian Armed Forces. The Ukrainian capital of Kyiv was among the major cities hit, along with areas of Kharkiv, Kherson, Cherkasy, Rivne and Lviv.

Ukrainian authorities were still assessing the damage and casualties on Thursday morning, but dozens of injuries have been reported so far. At least seven people were injured by falling debris in Kyiv.

Meanwhile, rescue efforts were ongoing in the central city of Cherkasy to evacuate as many as 20 people believed to be trapped beneath the rubble of a hotel that was destroyed in the strikes overnight. Thirteen others were already rescued and at least nine were injured, according to Ukrainian officials

The overnight strikes also targeted energy infrastructure in the Rivne region and an industrial zone in the Lviv area.

-ABC News' Victoria Beaulé, Guy Davies, Yulia Drozd and Tatyana Rymarenko.

Russian forces initiated six strikes on Kharkiv overnight, damaging civilian infrastructure, Ukrainian officials said early Thursday.

The mayor of Kyiv also said explosions occurred in the Ukrainian capital overnight. Debris from the downed rockets fell in the Darnytskyi and Holosiivskyi districts of the city.

Five people were hurt in the Darnytskyi district of Kyiv, where the strike also destroyed non-residential buildings. Three of them, including a 9-year-old girl, were hospitalized. Two were treated by medics on scene.

In the Shevchenkivskyi district of Kyiv, rocket debris damaged a gas pipe, an official said.

-ABC News' Will Gretsky

Seventeen people were killed, and 32 others injured, when a Russian missile hit a market in the center of Kostyantynivka in the Donetsk region, according to Ukrainian officials.

"At this moment, the artillery of Russian terrorists has killed 16 people in the city of Kostiantynivka, Donetsk region," President Volodymyr Zelenskyy said on Telegram. "A regular market. Shops. A pharmacy. People who did nothing wrong. Many wounded. Unfortunately, the number of casualties and the injured may rise."

Secretary of State Antony Blinken spoke Saturday with Turkish Foreign Minister Hakan Fidan to discuss the ongoing situation in Russia.

"Secretary Blinken reiterated that U.S. support for Ukraine will not change. The United States will stay in close coordination with Allies and partners as the situation develops," spokesperson Matthew Miller said.

Blinken also spoke with Ukrainian Foreign Minister Dmytro Kuleba on Saturday to discuss the situation in Russia, Miller said. Blinken reiterated that support by the U.S. for Ukraine will not change.

The U.S. will stay in close coordination with Ukraine as the situation develops.

-ABC News Shannon K. Crawford