"I'll be very blunt," Biden said on CBS' "60 Minutes." "If I thought we could've put together the campaign that, that our supporters deserve and our contributors deserved ... I would have gone ahead and done it."
Biden announced Wednesday that he would not launch a third bid for the White House, after months of weighing whether his family had the emotional energy to run following the death of his son Beau in May.
"It doesn't follow schedules of primaries and caucuses and contributors and the like," he said of his grief. "Everybody grieves at a different pace.
"I've said from the beginning that I don't know whether our ability to deal with the loss of Beau would reach a point where we could do that before time ran out," he said. "There was nothing we could control."
In the interview, the vice president disputed a story that his son asked him to run for president on his deathbed.
"Beau all along thought that I should run and I could win," he said. "But there was not what was sort of made out as kind of this Hollywood-esque thing that at the last minute Beau grabbed my hand and said, 'Dad, you've got to run, like, win one for the Gipper.' It wasn't anything like that."
"I like Hillary. Hillary and I get along together," he said. "The only reason to run is because I -- I still think I could do a better job than anybody else could do. That's the reason to run. I wouldn't run against Hillary."
"That wasn't directed at Hillary," Biden said of his comments. "That was a reference to Washington. All of Washington."
The vice president said that during his last year in the White House he hopes to focus on enhancing cancer research.
"I think I'm still moving up. I think we got a lot to do," he said.