Both programs have announced alternative uniforms for the game that will feature an all-maize look for the Wolverines.
The maize uniforms, provided by the Jordan Brand, are in celebration of the university's bicentennial and in honor of the 150th anniversary of the school's colors, according to a university release.
This will be the second time Michigan has donned an all-maize uniform, first worn in 1928 against Navy.
Florida will be wearing an all-blue version of Nike's color rush uniforms that have been used as NFL alternative jerseys in the past.
The Gators will wear all-blue uniforms, gloves, cleats, socks and wristbands. The university called it a subtle yet bold change from its traditional look.
Saturday's game is set for 3:30 p.m. ET on ABC.