An 80-year-old woman who was trapped in her home is the third fatality from historic floods overwhelming parts of the Midwest.
At least 16 rivers are flooding, with the worst along the Nebraska and Iowa border.
One reason the flooding is so severe is because of the region's massive snow accumulations and sudden rise in temperatures.
The dangerous flooding, caused by snow melt, ice jams and last week's rainfall, washed away roads and bridges, isolating some communities.
A Nebraska man died when he drove around a barricade and was swept away in his vehicle, The Associated Press reported.
A Nebraska farmer died when he was trying to reach stranded drivers and a bridge collapsed, the AP said.
The body of 80-year-old Betty Hamernik was found in her home in rural Columbus, Nebraska, according to the Platte County Sheriff's Office.
Over 100 people have been rescued and more than 870 are staying in shelters, according to officials with Nebraska's Office of Emergency Management.
Some of the worst flooding is receding Monday, but other areas, especially from Nebraska City, Nebraska, to St. Joseph, Missouri, will see river flooding continue this week.
One third of the structures at Nebraska's Offutt Air Force Base are underwater, a spokesperson told ABC News Monday.
In a bit of good news, the Platte and Elkhorn rivers near Omaha were quickly receding Monday morning. Both of those rivers had crested this weekend, breaking records from the 1960s.
River flooding is also ongoing in other parts of the Midwest.
In Joslin, Illinois, near Quad Cities, the Rock River is cresting below a record but will remain in the major flood stage for much of this week.