There were 1,984 fatalities from COVID-19 registered in the United States on Wednesday, according to a real-time count kept by Johns Hopkins University.

The latest daily death toll is the highest figure since early May but still under the country's peak of 2,609 new deaths on April 15.

An additional 144,133 cases of COVID-19 were also identified nationwide on Wednesday, marking a new single-day record.

It's the eighth day in a row that the country has reported over 100,000 new infections. Wednesday's tally tops the nation's previous all-time high of 136,325 new cases recorded a day earlier.

A total of 10,257,825 people in the United States have been diagnosed with COVID-19 since the pandemic began, and at least 239,683 of them have died, according to Johns Hopkins. The cases include people from all 50 U.S. states, Washington, D.C. and other U.S. territories as well as repatriated citizens.

Much of the country was under lockdown by the end of March as the first wave of pandemic hit. By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country's cases then hovered around 20,000 for a couple of weeks before shooting back up and crossing 100,000 for the first time on Nov. 4.

Should it be authorized, Pfizer's coronavirus vaccine needs to be kept at extremely cold temperatures -- which could pose a challenge in distributing doses across the country, pharmaceutical experts said Wednesday on ABC News Live Prime.

The freezers needed to properly store Pfizer's vaccine at around minus 70 degrees Celsius are "almost like unicorns in health care -- they're far and hard to find," Soumi Saha, senior director of pharmacy consulting company Premier, Inc., told ABCNL.

"[It's] the coldest that any vaccine or any drug has ever been required to be stored at," Saha said. "And so this is going to be the greatest drug distribution challenge that our country has ever faced because of the unique circumstances around the temperature requirement."

Keeping Pfizer's vaccine stable when distributing it in rural communities might pose another challenge, according to Azra Behlim, senior director of pharmacy sourcing and program services at Vizient.

"That is going to be a lot more difficult, because now we need to find a way to maintain that temperature while we are driving it out 20 or 50 miles in order to do an inoculation," Behlim told ABCNL.

Earlier this week, Pfizer and partner Biotech announced that their vaccine was "found to be more than 90% effective in preventing COVID-19" based on an early analysis that included 94 confirmed cases of COVID-19 in trial participants. More safety data is needed prior to authorization.

Pfizer has committed to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021.

The company will distribute vaccine doses in special temperature-controlled thermal boxes packed with dry ice. Most will go from its Kalamazoo, Michigan, site directly to places where the vaccines are needed.

Upon reaching their destination, the doses can be repacked with dry ice and stored for up to 15 days, stored in normal refrigerators for up to five days or kept in ultra-low-temperature freezers for up to six months. These freezers are typically only available at large medical centers.

ABC News' Sony Salzman, Victor Ordonez and Layne Winn

The U.S. reported a record 144,270 daily COVID-19 cases on Wednesday, according to The COVID Tracking Project.

It marked the first time the number of new cases nationally crossed 140,000. The figure also broke a record set the day before by more than 13,000 cases, based on data from the tracker.

There were 1,421 deaths due to COVID-19 reported on Wednesday.

Last month, 8.4% of long-term care facility residents diagnosed with COVID-19 died, according to The COVID Tracking Project, as the surge in coronavirus cases takes its toll on the vulnerable population.

That percentage is about seven times the national rate, according to the data project, which is now publishing weekly updates on the state of the pandemic in long-term care facilities.

The project tracked more than 24,000 new cases in long-term care facilities last week. About one-fifth, it said, were in Indiana, Ohio and Pennsylvania.

"Because a case in a long-term care facility is far more likely to result in death, this explosion in cases is alarming," the project said.

Indeed, from Oct. 29 to Nov. 5, long-term care facilities accounted for 4% of the nation's COVID-19 cases, but 39% of the nation's deaths, according to the project.

That number was even higher in South Dakota, where 73% of deaths that occurred in the state during that time frame were among long-term care residents, it said.