Coronavirus updates: 'Close contact' definition updated by CDC

The CDC offered new, more strict guidance on Wednesday.

A pandemic of the novel coronavirus has now killed more than 1.1 million people worldwide.

Over 41.1 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country to country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 8.3 million diagnosed cases and at least 221,987 deaths.

California has the most cases of any U.S. state, with more than 886,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 868,000 cases and over 760,000 cases, respectively.

Nearly 200 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


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COVID-19 cases among US children surge 13%, new report says

The number of children diagnosed with COVID-19 across the United States increased by 13% in the first two weeks of October, according to a new report from the American Academy of Pediatrics and the Children’s Hospital Association.

There were 84,319 pediatric cases of COVID-19 reported nationwide from Oct. 1 to Oct. 15. The overall rate of infection is 986 cases per 100,000 children in the population, according to the weekly report, which was published Tuesday.

"While children represented only 10.9% of all cases in states reporting cases by age, over 741,000 children have tested positive for COVID-19 since the onset of the pandemic," the report said.

Even so, the report noted that severe illness and deaths due to COVID-19 appear to be rare among children at this time. As of Oct. 15, children accounted for 1%-3.6% of total reported hospitalizations and 0%-0.27% of all COVID-19 deaths in the United States. Fourteen states reported zero pediatric deaths from the disease, according to the report.

"However, states should continue to provide detailed reports on COVID-19 cases, testing, hospitalizations, and mortality by age and race/ethnicity so that the effects of COVID-19 on children’s health can be documented and monitored," the report said.


Analysis shows rise in COVID-19 hospitalizations in 42 US states

An ABC News analysis of COVID-19 trends across all 50 U.S. states as well as Washington, D.C. and Puerto Rico found there were increases in hospitalizations over the past two weeks in 42 states.

The analysis also found increases in newly confirmed cases of COVID-19 in 40 states plus Puerto Rico, increases in the daily positivity rate of COVID-19 tests in 27 states and increases in daily COVID-19 death tolls in 17 states.

Since Oct. 1, there have been 972,902 cases reported nationwide. More than 400,000 of those cases have been reported in just the last seven days. The country is on track this week to exceed 1 million cases for the month of October, making it the fourth month on record to surpass the grim milestone.

Cases are undoubtably surging nationally. The United States is currently averaging 57,000 new cases a day -- the highest it has been in 11 weeks. That average has increased by 67% since Sept. 12.

Two states -- Kansas and Tennessee -- hit a record number of new cases reported in a 24-hour reporting period, while five states -- Kentucky, Montana, Nebraska, Ohio and Wyoming -- saw a record number of current hospitalizations in a day.

The trends were all analyzed from data collected and published by the COVID Tracking Project over the past two weeks, using the linear regression trend line of the seven-day moving average to examine whether a state's key indicators were increasing, decreasing or remained flat.

ABC News' Benjamin Bell, Brian Hartman, Soorin Kim and Arielle Mitropolous contributed to this report.