Coronavirus updates: 'Close contact' definition updated by CDC

The CDC offered new, more strict guidance on Wednesday.

A pandemic of the novel coronavirus has now killed more than 1.1 million people worldwide.

Over 41.1 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country to country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 8.3 million diagnosed cases and at least 221,987 deaths.

California has the most cases of any U.S. state, with more than 886,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 868,000 cases and over 760,000 cases, respectively.

Nearly 200 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


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COVID-19 cases among US children surge 13%, new report says

The number of children diagnosed with COVID-19 across the United States increased by 13% in the first two weeks of October, according to a new report from the American Academy of Pediatrics and the Children’s Hospital Association.

There were 84,319 pediatric cases of COVID-19 reported nationwide from Oct. 1 to Oct. 15. The overall rate of infection is 986 cases per 100,000 children in the population, according to the weekly report, which was published Tuesday.

"While children represented only 10.9% of all cases in states reporting cases by age, over 741,000 children have tested positive for COVID-19 since the onset of the pandemic," the report said.

Even so, the report noted that severe illness and deaths due to COVID-19 appear to be rare among children at this time. As of Oct. 15, children accounted for 1%-3.6% of total reported hospitalizations and 0%-0.27% of all COVID-19 deaths in the United States. Fourteen states reported zero pediatric deaths from the disease, according to the report.

"However, states should continue to provide detailed reports on COVID-19 cases, testing, hospitalizations, and mortality by age and race/ethnicity so that the effects of COVID-19 on children’s health can be documented and monitored," the report said.


Boston Public Schools to suspend in-person learning amid rising positivity rates

Boston will suspend all in-person learning for its public school system, effective this Thursday, Superintendent Brenda Cassellius announced on Wednesday in a letter to employees obtained by ABC News' local affiliate WCVB.

The move came after local health officials said that the citywide seven-day COVID-19 positivity rate had increased to 5.7% -- a jump from 4.5% last week, and 4.1% two weeks before.

“We remain committed to providing in-person learning opportunities to our students as soon as it is safe to do so, and will continue to prioritize out students with the highest needs for in-person learning,” Cassellius wrote.

Boston will resume in-person learning for high-need students in public schools once the seven-day positivity rate is below 5% for two consecutive weeks. A phased-in approach will also begin for the districts youngest students when the positivity rate is below 4% for two consecutive weeks.

The seven-day average of new cases in Massachusetts has been on the rise for nearly seven weeks, increasing by 86% just in the last month.

ABC News' Arielle Mitropoulos contributed to this report.