Coronavirus updates: FDA OKs remdesivir as 1st approved treatment in US

Remdesivir had already received emergency use authorization.

A pandemic of the novel coronavirus has now killed more than 1.1 million people worldwide.

Over 41.5 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country to country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 8.4 million diagnosed cases and at least 223,000 deaths.

California has the most cases of any U.S. state, with more than 893,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 871,000 cases and over 768,000 cases, respectively.

Nearly 200 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


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US reports highest daily death toll since mid-September

An additional 1,124 fatalities from COVID-19 were registered in the United States on Wednesday, according to a real-time count kept by Johns Hopkins University.

The latest daily death toll is the highest the country has reported since Sept. 15 but still less than the record 2,666 new fatalities registered on April 17.

There were also 62,735 new cases of COVID-19 identified nationwide Wednesday, up by more than 2,000 from the previous day but down from a peak of 77,255 new cases on July 16.

A total of 8,337,204 people in the United States have been diagnosed with COVID-19 since the pandemic began, and at least 222,201 of them have died, according to Johns Hopkins. The cases include people from all 50 U.S. states, Washington, D.C. and other U.S. territories as well as repatriated citizens.

By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country's cases then hovered around 20,000 for a couple of weeks before shooting back up and crossing 70,000 for the first time in mid-July.

The daily tally of new cases has gradually come down since then but has started to climb again in recent weeks and is now averaging around 60,000 per day.


COVID-19 patients fill up 60% of ICU beds in greater Paris region

COVID-19 patients now take up more than 60% of all intensive care unit beds in hospitals across the greater Paris region of Ile-de-France, a spokesperson for the regional health agency told ABC News.

That figure is up from 59.3% on Tuesday.

There were 669 COVID-19 patients listed in critical condition as of Wednesday night, according to the spokesperson.

France is among several countries in Europe seeing a rise in COVID-19 infections as a second wave of the pandemic hits the region.

So far, France's public health agency has confirmed a total of 957,421 cases, including at least 34,048 deaths. The country has the seventh-highest case count in the world, according to a tally kept by Johns Hopkins University.

ABC News' Ibtissem Guenfoud contributed to this report.