Coronavirus updates: 'Close contact' definition updated by CDC

The CDC offered new, more strict guidance on Wednesday.

A pandemic of the novel coronavirus has now killed more than 1.1 million people worldwide.

Over 41.1 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country to country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 8.3 million diagnosed cases and at least 221,987 deaths.

California has the most cases of any U.S. state, with more than 886,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 868,000 cases and over 760,000 cases, respectively.

Nearly 200 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


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COVID-19 cases among US children surge 13%, new report says

The number of children diagnosed with COVID-19 across the United States increased by 13% in the first two weeks of October, according to a new report from the American Academy of Pediatrics and the Children’s Hospital Association.

There were 84,319 pediatric cases of COVID-19 reported nationwide from Oct. 1 to Oct. 15. The overall rate of infection is 986 cases per 100,000 children in the population, according to the weekly report, which was published Tuesday.

"While children represented only 10.9% of all cases in states reporting cases by age, over 741,000 children have tested positive for COVID-19 since the onset of the pandemic," the report said.

Even so, the report noted that severe illness and deaths due to COVID-19 appear to be rare among children at this time. As of Oct. 15, children accounted for 1%-3.6% of total reported hospitalizations and 0%-0.27% of all COVID-19 deaths in the United States. Fourteen states reported zero pediatric deaths from the disease, according to the report.

"However, states should continue to provide detailed reports on COVID-19 cases, testing, hospitalizations, and mortality by age and race/ethnicity so that the effects of COVID-19 on children’s health can be documented and monitored," the report said.


Czech Republic reports nearly 12,000 new cases in record high

The Czech Republic confirmed 11,984 new cases of COVID-19 on Tuesday, a new record for the Central European country.

The Czech Republic has shattered its own record already several times this month. The country's previous record of 11,105 new cases was set last Friday.

The cumulative total now stands at 193,946 cases, about one third of which were registered in the past seven days, according to data from the Czech health ministry.

More than 113,000 cases were active, including 4,064 patients who remained hospitalized for COVID-19, while over 79,000 have recovered from the disease, according to the health ministry data.

So far, 1,619 people have died from the disease in the Czech Republic. The country's highest single-day death toll of 97 was recorded on Monday, according to the health ministry data.

The Czech Republic has the highest rate of COVID-19 infection in Europe. Over the past two weeks, the country of 10.7 million people has reported 975.8 cases per 100,000 population, according to data published Wednesday by the European Center for Disease Prevention and Control.

New restrictive measures, including mandatory mask-wearing outdoors and in cars, are slated to take force across the Czech Republic on Wednesday. The government was expected to meet early Wednesday to discuss additional measures.