Coronavirus updates: FDA OKs remdesivir as 1st approved treatment in US

Remdesivir had already received emergency use authorization.

A pandemic of the novel coronavirus has now killed more than 1.1 million people worldwide.

Over 41.5 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country to country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 8.4 million diagnosed cases and at least 223,000 deaths.

California has the most cases of any U.S. state, with more than 893,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 871,000 cases and over 768,000 cases, respectively.

Nearly 200 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


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US reports highest daily death toll since mid-September

An additional 1,124 fatalities from COVID-19 were registered in the United States on Wednesday, according to a real-time count kept by Johns Hopkins University.

The latest daily death toll is the highest the country has reported since Sept. 15 but still less than the record 2,666 new fatalities registered on April 17.

There were also 62,735 new cases of COVID-19 identified nationwide Wednesday, up by more than 2,000 from the previous day but down from a peak of 77,255 new cases on July 16.

A total of 8,337,204 people in the United States have been diagnosed with COVID-19 since the pandemic began, and at least 222,201 of them have died, according to Johns Hopkins. The cases include people from all 50 U.S. states, Washington, D.C. and other U.S. territories as well as repatriated citizens.

By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country's cases then hovered around 20,000 for a couple of weeks before shooting back up and crossing 70,000 for the first time in mid-July.

The daily tally of new cases has gradually come down since then but has started to climb again in recent weeks and is now averaging around 60,000 per day.


Czech Republic sees another record surge in new cases as restrictions tighten

The Czech Republic confirmed 14,968 new cases of COVID-19 on Wednesday, setting a new record for the second straight day.

The country's cumulative total now stands at 208,915 confirmed cases, about a third of which have been registered in last seven days. More than 124,000 cases were active, including 4,417 patients who remained hospitalized for COVID-19, while over 83,000 have recovered from the disease, according to data from the Czech health ministry.

So far, 1,739 people have died from the disease in the Czech Republic. The country's highest single-day death toll of 97 was recorded on Monday, according to the health ministry data.

The Czech Republic has the highest rate of COVID-19 infection in Europe. Over the past two weeks, the nation of 10.7 million people has reported 1,066.3 cases per 100,000 population, according to data published Thursday by the European Center for Disease Prevention and Control.

New restrictive measures, including mandatory mask-wearing outdoors and in cars, went into effect across the Czech Republic on Wednesday. Further restrictions, such as limits on movement and the closure of many businesses, will be imposed Thursday.