Coronavirus updates: FDA OKs remdesivir as 1st approved treatment in US

Remdesivir had already received emergency use authorization.

A pandemic of the novel coronavirus has now killed more than 1.1 million people worldwide.

Over 41.5 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country to country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 8.4 million diagnosed cases and at least 223,000 deaths.

California has the most cases of any U.S. state, with more than 893,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 871,000 cases and over 768,000 cases, respectively.

Nearly 200 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


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Belgium's foreign minister admitted to ICU for COVID-19

Belgian Foreign Minister Sophie Wilmes was hospitalized for COVID-19 and admitted to an intensive care unit on Wednesday evening, a spokesperson told ABC News.

The 45-year-old's condition remains stable, the spokesperson said.

Wilmes, who was the caretaker prime minister of Belgium during the first wave of the coronavirus pandemic, announced via Twitter on Saturday that she had tested positive for COVID-19, saying that the "contamination probably happened within my family circle given all precautions taken outside of my home."

She is the country's first woman foreign minister, as well as the first and only woman prime minister in Belgian history.

ABC News' Aicha El Hammar Castano contributed to this report.


Czech Republic sees another record surge in new cases as restrictions tighten

The Czech Republic confirmed 14,968 new cases of COVID-19 on Wednesday, setting a new record for the second straight day.

The country's cumulative total now stands at 208,915 confirmed cases, about a third of which have been registered in last seven days. More than 124,000 cases were active, including 4,417 patients who remained hospitalized for COVID-19, while over 83,000 have recovered from the disease, according to data from the Czech health ministry.

So far, 1,739 people have died from the disease in the Czech Republic. The country's highest single-day death toll of 97 was recorded on Monday, according to the health ministry data.

The Czech Republic has the highest rate of COVID-19 infection in Europe. Over the past two weeks, the nation of 10.7 million people has reported 1,066.3 cases per 100,000 population, according to data published Thursday by the European Center for Disease Prevention and Control.

New restrictive measures, including mandatory mask-wearing outdoors and in cars, went into effect across the Czech Republic on Wednesday. Further restrictions, such as limits on movement and the closure of many businesses, will be imposed Thursday.


COVID-19 patients fill up 60% of ICU beds in greater Paris region

COVID-19 patients now take up more than 60% of all intensive care unit beds in hospitals across the greater Paris region of Ile-de-France, a spokesperson for the regional health agency told ABC News.

That figure is up from 59.3% on Tuesday.

There were 669 COVID-19 patients listed in critical condition as of Wednesday night, according to the spokesperson.

France is among several countries in Europe seeing a rise in COVID-19 infections as a second wave of the pandemic hits the region.

So far, France's public health agency has confirmed a total of 957,421 cases, including at least 34,048 deaths. The country has the seventh-highest case count in the world, according to a tally kept by Johns Hopkins University.

ABC News' Ibtissem Guenfoud contributed to this report.


New cases up by double digits across US, HHS memo says

The number of new cases of COVID-19 recorded in the United States increased by double digits in week-over-week comparisons, while deaths and intensive care unit admissions are also on the rise, according to an internal memo from the U.S. Department of Health and Human Services that was obtained by ABC News on Wednesday night.

The memo, which is circulated among the highest levels of the federal government and is used to determine daily priorities for the agencies working on a COVID-19 response, said 41 U.S. states and territories are in an upward trajectory of new infections, while six jurisdictions are at a plateau and seven others are in a downward trend.

There were 414,004 new cases confirmed during the period of Oct. 14-20, a 15.1% increase from the previous week. There were also 5,168 fatalities from COVID-19 recorded during the same period, a 4.2% increase compared with the week prior, according to the memo.

The national positivity rate for COVID-19 tests dropped slightly from 6% to 5.8% in week-to-week comparisons. Meanwhile, 23% of hospitals nationwide have more than 80% of their ICU beds full. That figure was 17%-18% during the summertime peak, the memo said.

In Illinois, the number of new cases increased 41.1% on Oct. 18 compared to the prior week, over twice the national growth in infections -- 14.8% -- during the same period. Meanwhile, COVID-19 hospitalizations continued to climb, with the state reporting a seven-day average of 17.3 hospitalizations per 100,000 people on Oct. 18. The state is also experiencing a shortage of health care professionals, particularly nurses, according to the memo.

Indiana saw a 22.4% increase in new cases and an 8% uptick in new deaths between the weeks ending Oct. 11-18. The state reported a record high of 2,521 new cases on Oct 17, one day after surpassing a daily tally of 2,000 new cases for the first time. The state also reported its highest seven-day average of COVID-19 hospitalizations -- 20.1 per 100,000 people on Oct. 18. During that time, an average of 63% of inpatient beds and 66.4% of ICU beds were full. Indiana has reissued a call for retired health care professionals to volunteer as hospitals across the state face staffing issues, the memo said.

Michigan's Washtenaw County saw a relative increase of 110.9% in new cases between Oct. 11-18. The surge may be driven by the University of Michigan, where the school's quarantine and isolation housing was at 52.8% occupancy as of Oct. 20, according to the memo.

Minnesota reported a record high of 126 new COVID-19 hospitalizations on Oct. 20. The number of new cases increased 24.9% across the state in the week ending Oct. 19, while new deaths climbed by 53.5%, the memo said.

North Dakota reported 587 new cases per 100,000 people in the last week, the highest rate in the country, compared to a national average of 117 per 100,000 people, according to the memo.

Ohio registered 2,234 new cases on Oct. 17, its highest number since the coronavirus pandemic and marking the fourth straight day the state's daily tally was over 2,000. Ohio also reported a record high of 1,145 COVID-19 hospitalizations on Oct. 19. The state's seven-day average of hospitalizations has continued to climb over the past three months, reaching a rate of 13.2 per 100,000 population on Oct. 18, the memo said.

ABC News' Josh Margolin contributed to this report.


Fauci suggests kids trick-or-treat by saying hello to neighbors

Dr. Anthony Fauci is suggesting a new twist on trick-or-treating during the pandemic.

Fauci, director of the National Institute of Allergy and Infectious Diseases, recommends kids in costume go to a neighbors home, knock on the door and stay six or more feet away.

"Wear a mask, say hello," Fauci said in a livestream interview last week with Chrisi Grimm, the principal deputy inspector general for Health and Human Services.

But when it comes to the question of accepting candy, Fauci may disappoint the kids of America.

"The question of taking things like candy and stuff. You know, to me, it would be just. ‘Hello, I'm giving you a virtual trick-or-treat,' as opposed to getting involved in people that you don't know,” he said.

ABC News' Anne Flaherty and Sarah Kolinovsky contributed to this report.