Coronavirus updates: Barron Trump also tested positive for COVID, Melania says

Melania Trump said she and her son have now tested negative.

A pandemic of the novel coronavirus has now killed more than 1 million people worldwide.

Over 38.4 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country-to-country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 7.9 million diagnosed cases and at least 216,639 deaths.

California has the most cases of any U.S. state, with more than 865,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 830,000 cases and over 741,000 cases, respectively.

More than 190 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


0

Analysis shows cases rising in 35 US states plus DC

An ABC News analysis of COVID-19 trends across all 50 U.S. states as well as Washington, D.C. and Puerto Rico found there were increases in newly confirmed cases over the past two weeks in 35 states as well as the nation's capital.

The analysis also found increases in the daily positivity rate of COVID-19 tests in 24 states plus D.C., increases in COVID-19 hospitalizations in 36 states and increases in daily COVID-19 death tolls in 11 states plus Puerto Rico.

The seven-day average of new cases in the United States has now surpassed 51,000, the highest it has been in nearly two months.

Six states -- Iowa, Montana, Oklahoma, South Dakota, Wisconsin and West Virginia -- hit a record number of current COVID-19 hospitalizations in a day. One state -- Wisconsin -- reported its highest single-day increase in the number of new COVID-19 cases and also hit a peak of new deaths from the disease.

The trends were all analyzed from data collected and published by the COVID Tracking Project over the past two weeks, using the linear regression trend line of the seven-day moving average to examine whether a state's key indicators were increasing, decreasing or remained flat.

ABC News' Benjamin Bell, Brian Hartman, Soorin Kim and Arielle Mitropolous contributed to this report.


ICU admissions jump by 13.7% in Italy

The number of patients admitted to intensive care units in Italy has jumped by 13.7% within the past 24 hours, as COVID-19 infections surge again in the country where the pandemic first took hold in Europe.

Italy's civil protection agency confirmed 5,901 new cases of COVID-19 on Tuesday, an increase of 1,282 from the previous day. An additional 41 deaths from COVID-19 were also registered, the country's worst single-day death toll from the disease since June 17.

The cumulative totals now stand at 365,467 cases and 36,246 deaths.

Italy, once the epicenter of the coronavirus pandemic, introduced strict new nationwide measures on Tuesday after seeing a sharp uptick in cases in recent weeks.

The European country had gradually loosened restrictions during the spring and summer, following a nearly three-month lockdown that helped get its COVID-19 outbreak under control.

ABC News' Phoebe Natanson contributed to this report.


Man suffers sudden hearing loss due to COVID-19 in 1st such case in UK

A 45-year-old British man has suffered sudden complete hearing loss while being treated for COVID-19, which doctors say is the first such case in the United Kingdom.

A case study published Tuesday in the British Medical Journal’s BMJ Case Reports said the man, who has asthma but is otherwise "fit and well," was hospitalized several days after developing COVID-19 symptoms. He was subsequently placed on a ventilator and transferred to the intensive care unit, where he remained intubated for 30 days.

The patient received remdesivir, intravenous steroids and plasma exchange to treat his COVID-19 infection, which clinically improved. A week after being taken off the ventilator and transferring out of the ICU, the man noticed ringing in his left ear followed by sudden onset hearing loss. He had no previous history of hearing loss or ear pathology, according to the case study.

Following a week of hearing loss, the patient saw an otolaryngology specialist and was treated with steroids. His hearing partially recovered after completing a seven-day course, according to the case study.

The researchers -- from the University College London and Royal National Throat Nose and Ear Hospital -- noted that there are only a few other reported cases of hearing loss following COVID-19 infection.

"This is the first reported case of sensorineural hearing loss following COVID-19 infection in the U.K.," the researchers wrote. "Given the widespread presence of the virus in the population and the significant morbidity of hearing loss, it is important to investigate this further."


Chinese city tests more than 8 million residents amid outbreak

The eastern Chinese port city of Qingdao has tested almost all of its 9 million residents for COVID-19 since launching a citywide testing campaign this week, amid the country's first reported domestic outbreak in months.

The Qingdao Municipal Health Commission said in a statement Wednesday that it had collected over 8.2 million samples for COVID-19 tests and that no new cases have been found among the results returned thus far. The entire city will be tested this week, the commission said.

A total of 12 cases of COVID-19 -- six with symptoms and six without -- have been recorded in Qingdao, since an outbreak linked to the city's Municipal Chest Hospital was discovered over the weekend. As of Wednesday, 532 close contacts have been investigated in the city, all of whom have been quarantined and observed and completed two rounds of testing, according to the Qingdao Municipal Health Commission.

The Chinese mainland, where the coronavirus pandemic began last December, has so far reported 85,611 confirmed cases of COVID-19 and 4,634 deaths, including 13 new cases of local transmission and 14 cases brought from outside the country, according data released Wednesday by China's National Health Commission. The country does not count asymptomatic infections as confirmed cases.


New cases in US rise by double digits in week-over-week comparisons

The number of new COVID-19 cases recorded in the United States increased by double digits in week-over-week comparisons, while the number of new deaths from the disease continued to tick downward slightly, according to an internal memo from the U.S. Department of Health and Human Services that was obtained by ABC News on Tuesday night.

The memo, which is circulated to the highest levels of the federal government and is used to determine daily priorities for the agencies working on COVID-19 response, said 34 U.S. states and territories are in an upward trajectory of new infections, while 10 jurisdictions are at a plateau and 12 others are in a downward trend.

There were 351,270 new cases confirmed during the period of Oct. 6-Oct. 12, a 14.4% increase from the previous week. There were also 4,886 fatalities from COVID-19 recorded during the same period, a 1.5% decrease compared with the week prior. The national positivity rate for COVID-19 tests increased from 4.7% to 6.1% in week-to-week comparisons, according to the memo.

Meanwhile, 22% of hospitals nationwide have more than 80% of beds full in their intensive care units. That figure was 17-18% during the summertime peak, the memo said.

California's Sonoma County saw a 129.7% relative increase in new cases of COVID-19 between Sept. 29 and Oct. 6. The county confirmed 62 cases on Oct. 7 linked to outbreaks at schools and childcare facilities, according to the memo.

Kentucky reported on Oct. 7 its highest number of COVID-19 patients in ICUs since May. As of Oct. 6, the state's seven-day average for ICU bed occupancy was 80.6%, with 43.7% of adult ICU beds occupied by COVID-19 patients, the memo said.

Montana hit a peak of 504 new COVID-19 cases confirmed on Oct. 6. Daily hospital admissions in the state have increased from 40 in mid-September to more than 60 per day, with greater than 80 on Oct. 5 and Oct. 6. Montana's seven-day hospitalization rate continues to rise from 15.7 per 100,000 population on sept. 29 to a four-month high of 20 per 100,000 population on Oct. 6. Local officials report that hospitals are closed to or at capacity and have started redirecting patients, according to the memo.

New Jersey's seven-day COVID-19 case rate increased 20.6% to 539.5 cases per 1 million population between Sept. 29 and Oct. 6. The state has 71.7% of inpatient hospital beds occupied, with 56.4% of ICU beds full. At least 100 schools in New Jersey have teachers or students who have tested positive for COVID-19, the memo said.

New York recorded on Oct. 6 its highest number of total hospitalizations since July 22. The state has 79.5% of inpatient hospital beds occupied, with 62.4% of ICU beds full.

Utah reported more than 1,000 COVID-19 cases per day for six of the seven days last week. At the same time, week-to-week testing in the state has decreased slightly by 1.2%. Utah's positivity rate for COVID-19 tests, however, has remained stable at 14%.

ABC News' Josh Margolin contributed to this report.