Coronavirus updates: Trump says 'not much' he'd change about COVID response

Thirty-one states are considered in the red zone for new cases in the last week.

A pandemic of the novel coronavirus has now killed more than 1.1 million people worldwide.

Over 40.7 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country to country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 8.2 million diagnosed cases and at least 220,955 deaths.

California has the most cases of any U.S. state, with more than 883,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 862,000 cases and over 760,000 cases, respectively.

More than 190 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


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COVID-19 patients in hospitals 5 times more likely to die than those hospitalized with flu, CDC says

Patients hospitalized with COVID-19 are five times more likely to die compared to patients hospitalized with the flu, according to a Centers for Disease Control and Prevention study. They were also more likely to need more time in the hospital to recuperate, and to develop medical complications like blood clots.

Among patients with COVID-19, the risk for certain complications, including respiratory and kidney problems, was higher for Black and Hispanic patients compared to white patients.

The study, however, was only among hospitals from within the Veterans Health Administration, so it may not be directly applicable across other hospital settings.

ABC News' Sony Salzman contributed to this report.


Ohio reports record high number of new hospitalizations

Ohio reported 216 new hospitalizations in the last 24 hours -- a record high for the state, Gov. Mike DeWine said Tuesday.

Ohio now has a total of 17,388 patients with COVID-19 in hospitals, according to state data.

"In the past day, 2,015 new cases have been reported in Ohio, and our numbers continue to rise at a rate that should concern all of us," the governor tweeted.

Ohio has over 185,000 people diagnosed with COVID-19. At least 5,083 have died.


Cuomo discourages New Yorkers from unnecessary travel to NJ, PA, CT

In New York, where the statewide positivity rate is 1.3%, neighboring states Connecticut, New Jersey and Pennsylvania now meet the criteria for New York's growing list of states on its travel advisory, Gov. Andrew Cuomo said Tuesday.

Because "there is no practical way to quarantine New York from Pennsylvania, New Jersey and Connecticut," the states won't be added to the list, Cuomo said in a statement. However, the governor said he's discouraging nonessential travel between the states.

New York's travel advisory requires people coming to the Empire State to quarantine for two weeks if they're arriving from a state with a positive test rate higher than 10 per 100,000 residents over a one-week average or an area with a 10% or higher positivity rate over a one-week rolling average.

These are the states and territories currently on New York's list: Alaska, Alabama, Arkansas, Arizona, Colorado, Delaware, Florida, Georgia, Guam, Iowa, Idaho, Illinois, Indiana, Kansas, Kentucky, Louisiana, Maryland, Michigan, Minnesota, Missouri, Mississippi, Montana, North Carolina, North Dakota, Nebraska, New Mexico, Nevada, Ohio, Oklahoma, Puerto Rico, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Wisconsin, West Virginia and Wyoming.

ABC News' J. Gabriel Ware contributed to this report.


More states in 'red zone,' per White House task force

Thirty-one states are considered in the red zone for new cases over the last week, indicating more than 100 new cases per 100,000 population, according to the White House coronavirus task force’s weekly briefing for governors, dated Oct. 18.

This is up from 26 states listed in the red zone in the previous week’s briefing, which was up from 24 states the week before.

Fourteen states and Washington, D.C. are in the orange zone over the last week, indicating between 51 and 100 new cases per 100,000 population.

Five states are in the yellow zone, indicating between 10 and 100 new cases per 100,000 population over the last week.

ABC News' Josh Margolin and Arielle Mitropoulos contributed to this report.


UK to launch controversial vaccine trials where volunteers will be infected

In a bid to speed up the race to find a vaccine for the novel coronavirus, the U.K. government announced Tuesday morning that it will be launching some controversial vaccine studies known as challenge trials.

In a world first for COVID-19, young healthy volunteers will be vaccinated, then intentionally exposed to the potentially deadly virus in order to test vaccines in a controlled environment. Although some medical experts view them as ethically questionable, the benefit of challenge trials is that they can be completed in a much shorter timeframe than typical late-stage studies.

The experiment will take place in a quarantine ward of a hospital in north London. After inhaling a diluted dose of the virus, the trial participants will be closely monitored, thus enabling scientists and doctors to better understand the disease and how a vaccine can fight it.

"Human challenge studies can increase our understanding of COVID-19 in unique ways and accelerate development of the many potential new COVID-19 treatments and vaccines," said Dr. Chris Chiu of Imperial College London's Department of Infectious Disease, a lead researcher on the human challenge study.

ABC News' Zoe Magee contributed to this report.