Dr. Anthony Fauci, chief medical adviser to U.S. President Joe Biden, said new, more contagious variants of the novel coronavirus are the top concern in the country right now and that the next six weeks will be critical.

"We're going to be doing … a full-court press on non-pharmacologic interventions [like masks] as well as getting as much vaccine out as we possibly can," Fauci, who is also the director of the National Institute of Allergy and Infectious Diseases, said at the International Aids Society conference on Tuesday.

"It's a very stressful situation ... when you have that much virus circulating, you're going to get a lot of mutations, no doubt about it," he added. "It's almost a race of trying to suppress the level of replication before we get so many accumulation of both the South African and other mutants as well as mutants of our own."

ABC News’ Cheyenne Haslett contributed to this report.

Maryland has identified two more confirmed cases of the new, more contagious B1351 variant of the novel coronavirus, which was first detected in South Africa, Gov. Larry Hogan said Tuesday.

The two patients are Montgomery County residents who recently traveled abroad, according to Hogan.

"Contact tracing is underway, and close contacts are isolating," the governor wrote on Twitter.

Maryland’s first case of the South Africa variant, in the Baltimore region, was announced on Saturday.

"The B.1.351 variant has not been shown to cause more severe illness or increased risk of death, though it is believed to be more transmissible," Hogan tweeted. "Initial evidence suggests that vaccines are still likely to be protective against the variant."

Capt. Sir Thomas Moore, the 100-year-old British World War II veteran who garnered global attention for his fundraising efforts amid the pandemic, has died after contracting COVID-19.

His death was announced Tuesday on social media accounts run by his family.

Moore was being treated for pneumonia over the past few weeks. After testing positive for COVID-19 last week, the centenarian was hospitalized on Sunday because "he needed additional help with his breathing," his daughter said in a statement posted on Twitter.

Last spring, Moore raised over 37 million pounds ($50.7 million) for the United Kingdom's National Health Service by walking laps in his garden in England amid a nationwide lockdown. Queen Elizabeth II honored Moore's charity and service to the country with a promotion to honorary colonel, a social flyover and knighthood.

A Buckingham Palace spokesperson told ABC News the queen "is sending a private message of condolence" to Moore's family and that she "very much enjoyed" meeting them last year.

"Her thoughts, and those of the Royal Family, are with them, recognising the inspiration he provided for the whole nation and others across the world," the spokesperson said.

ABC News' Zoe Magee contributed to this report.

Andrew Yang, who ran for president of the United States in 2020 and is currently running to be mayor of New York City, has tested positive for COVID-19.

"After testing negative as recently as this weekend, today I took a COVID rapid test and received a positive result," Yang said in a statement through his campaign Tuesday.

Yang said he has mild symptoms and that, as he self-quarantines at home, he'll "continue to attend as many virtual events as possible."

"Our team has begun the contact tracing process to notify anyone who may have been in close contact with me," he added.

January marked the nation's deadliest month of the coronavirus pandemic, with a death total approximately four times the reported number of COVID-19 deaths recorded by the U.S. in any month between June and October 2020, according to an ABC News' analysis of data compiled by The COVID Tracking Project, a volunteer-run effort to track the U.S. outbreak.

In total, the virus has claimed the lives of over 440,000 people in the U.S., which translates to about 1 in every 747 Americans, according to an ABC News analysis of data collected by Johns Hopkins University.

The U.S. death toll is approximately 147 times the total lives lost during the terrorist attacks on Sept. 11, 2001, and is around 65% of the total number of deaths that were recorded nationwide during the 1918 influenza pandemic.

Although the country's seven-day average of daily COVID-19 deaths appears to be plateauing, the U.S. is still reporting an average of just over 3,100 new deaths from the disease per day, according to The COVID Tracking Project data.

More than 6 million COVID-19 infections were diagnosed nationwide during the month of January, making it the country's second-worst month of the pandemic in terms of confirmed cases, data shows.

Over the weekend, the country's cumulative tally of confirmed cases surpassed 26 million, which signifies that one in every 12 Americans has now tested positive for COVID-19. However, the national seven-day average of daily COVID-19 cases has dropped by 32.3%, the lowest average the country has seen since mid-November, according to The COVID Tracking Project data.

COVID-19 hospitalizations also continue to decline rapidly across the country. The number of COVID-19 patients currently hospitalized nationwide is the lowest since late November.

In total, more than 800,000 people have been hospitalized with COVID-19 in the U.S. since the start of the pandemic, according to The COVID Tracking Project data.

ABC News' Brian Hartman and Arielle Mitropoulos contributed to this report.