Coronavirus updates: Barron Trump also tested positive for COVID, Melania says

Melania Trump said she and her son have now tested negative.

A pandemic of the novel coronavirus has now killed more than 1 million people worldwide.

Over 38.4 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country-to-country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

The United States is the worst-affected country, with more than 7.9 million diagnosed cases and at least 216,639 deaths.

California has the most cases of any U.S. state, with more than 865,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 830,000 cases and over 741,000 cases, respectively.

More than 190 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.


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Analysis shows cases rising in 35 US states plus DC

An ABC News analysis of COVID-19 trends across all 50 U.S. states as well as Washington, D.C. and Puerto Rico found there were increases in newly confirmed cases over the past two weeks in 35 states as well as the nation's capital.

The analysis also found increases in the daily positivity rate of COVID-19 tests in 24 states plus D.C., increases in COVID-19 hospitalizations in 36 states and increases in daily COVID-19 death tolls in 11 states plus Puerto Rico.

The seven-day average of new cases in the United States has now surpassed 51,000, the highest it has been in nearly two months.

Six states -- Iowa, Montana, Oklahoma, South Dakota, Wisconsin and West Virginia -- hit a record number of current COVID-19 hospitalizations in a day. One state -- Wisconsin -- reported its highest single-day increase in the number of new COVID-19 cases and also hit a peak of new deaths from the disease.

The trends were all analyzed from data collected and published by the COVID Tracking Project over the past two weeks, using the linear regression trend line of the seven-day moving average to examine whether a state's key indicators were increasing, decreasing or remained flat.

ABC News' Benjamin Bell, Brian Hartman, Soorin Kim and Arielle Mitropolous contributed to this report.


ICU admissions jump by 13.7% in Italy

The number of patients admitted to intensive care units in Italy has jumped by 13.7% within the past 24 hours, as COVID-19 infections surge again in the country where the pandemic first took hold in Europe.

Italy's civil protection agency confirmed 5,901 new cases of COVID-19 on Tuesday, an increase of 1,282 from the previous day. An additional 41 deaths from COVID-19 were also registered, the country's worst single-day death toll from the disease since June 17.

The cumulative totals now stand at 365,467 cases and 36,246 deaths.

Italy, once the epicenter of the coronavirus pandemic, introduced strict new nationwide measures on Tuesday after seeing a sharp uptick in cases in recent weeks.

The European country had gradually loosened restrictions during the spring and summer, following a nearly three-month lockdown that helped get its COVID-19 outbreak under control.

ABC News' Phoebe Natanson contributed to this report.


Man suffers sudden hearing loss due to COVID-19 in 1st such case in UK

A 45-year-old British man has suffered sudden complete hearing loss while being treated for COVID-19, which doctors say is the first such case in the United Kingdom.

A case study published Tuesday in the British Medical Journal’s BMJ Case Reports said the man, who has asthma but is otherwise "fit and well," was hospitalized several days after developing COVID-19 symptoms. He was subsequently placed on a ventilator and transferred to the intensive care unit, where he remained intubated for 30 days.

The patient received remdesivir, intravenous steroids and plasma exchange to treat his COVID-19 infection, which clinically improved. A week after being taken off the ventilator and transferring out of the ICU, the man noticed ringing in his left ear followed by sudden onset hearing loss. He had no previous history of hearing loss or ear pathology, according to the case study.

Following a week of hearing loss, the patient saw an otolaryngology specialist and was treated with steroids. His hearing partially recovered after completing a seven-day course, according to the case study.

The researchers -- from the University College London and Royal National Throat Nose and Ear Hospital -- noted that there are only a few other reported cases of hearing loss following COVID-19 infection.

"This is the first reported case of sensorineural hearing loss following COVID-19 infection in the U.K.," the researchers wrote. "Given the widespread presence of the virus in the population and the significant morbidity of hearing loss, it is important to investigate this further."


Chinese city tests more than 8 million residents amid outbreak

The eastern Chinese port city of Qingdao has tested almost all of its 9 million residents for COVID-19 since launching a citywide testing campaign this week, amid the country's first reported domestic outbreak in months.

The Qingdao Municipal Health Commission said in a statement Wednesday that it had collected over 8.2 million samples for COVID-19 tests and that no new cases have been found among the results returned thus far. The entire city will be tested this week, the commission said.

A total of 12 cases of COVID-19 -- six with symptoms and six without -- have been recorded in Qingdao, since an outbreak linked to the city's Municipal Chest Hospital was discovered over the weekend. As of Wednesday, 532 close contacts have been investigated in the city, all of whom have been quarantined and observed and completed two rounds of testing, according to the Qingdao Municipal Health Commission.

The Chinese mainland, where the coronavirus pandemic began last December, has so far reported 85,611 confirmed cases of COVID-19 and 4,634 deaths, including 13 new cases of local transmission and 14 cases brought from outside the country, according data released Wednesday by China's National Health Commission. The country does not count asymptomatic infections as confirmed cases.


Wisconsin sees an increase of more than 3,000 cases in one day

The number of Wisconsin COVID-19 hospitalizations is at an all-time high, Wisconsin Department of Health Services Deputy Secretary Julie Willems Van Dijk told reporters at a news conference Wednesday.

The state saw an increase of 3,107 cases since yesterday, bringing the total number of confirmed cases in the state to 153,578.

Fifty-seven of 72 counties in Wisconsin are meeting the threshold of very high disease activity levels, Van Dijk said, and every region in the state has one or more hospitals reporting staff shortages.
The death toll in Wisconsin currently stands at 1,536.

ABC News’ Rachel Katz contributed to this report.