At a press conference with the Qatari prime minister, Secretary of State Antony Blinken discussed efforts to implement safe zones in Gaza and provide other humanitarian assistance, but did not shed additional light on efforts to evacuate Americans and other foreign nationals ahead of a potential Israeli ground incursion.

"When it comes to providing for civilians in Gaza, both ensuring that they can be out of harm's way and that they can have access to the support that they need -- the humanitarian assistance the food, the medicine, water -- our focus now is on helping to create safe zones. And we're doing that with leading international organizations, and we're doing that engaged with Israel," Blinken said.

But Blinken said that those efforts to help Palestinians were still being actively hindered by Hamas.

"Hamas continues to use innocent civilians as human shields," he said.

"We know the humanitarian situation is urgent. We're actively engaged with partners, including Qatar, to get aid to the those who need it," he said.

-ABC News' Shannon Crawford

Seventy people were killed and 200 were injured in an Israeli strike on a convoy of civilians heading from northern Gaza to central Gaza, according to the Palestinian government press office.

-ABC News' Will Gretsky

The first U.S. charter flight to evacuate Americans from Israel has departed the country and is now en route to Europe, John Kirby, spokesperson for the National Security Council, told reporters on Friday. Kirby didn’t provide the exact destination in Europe.

He said more flights are expected to depart "in the coming days" and that "the State Department will continue to organize these charter flights for as long as there is a demand from US citizens for departure assistance."

He said the U.S. is still exploring "other options" to expand evacuation capacity, which also includes an option by sea.

Kirby also spoke to the heightened alert across the U.S.

"I want to be completely and crystal clear on one thing: At this time, none of our intelligence agencies have any specific intelligence indicating a threat to the United States stemming from the Hamas terrorist attack in Israel," Kirby stressed.

-ABC News' Justin Gomez

Israeli special forces have been inside Gaza over the last few days trying to locate hostages, according to an Israel Defense Forces spokesperson.

"Infantry and armored forces searched and gathered in the area for findings that may help in the effort to locate the missing and thwarted terrorist infrastructure and terrorist cells found in the area, among which a cell of the terrorist organization Hamas fired anti-tank fire at Israeli territory," the IDF said. Israel's air force is continuing its attacks on Hamas in Gaza, the IDF said.

Israel said its alerted 120 families that their loved ones are held in Gaza.

As time dwindles ahead of an anticipated Israeli ground invasion of Gaza, the U.S. is calling on fleeing citizens to head toward the southern border crossing to Egypt.

"We have been working around the clock. We have an entire dedicated team that is working on nothing but this: helping American citizens who are in Gaza be able to get safe passage through the border crossing to Egypt," Jake Sullivan told ABC "This Week" co-anchor Martha Raddatz on Sunday.

The U.S. Embassy in Jerusalem on Sunday morning urged U.S. citizens trapped in the Gaza Strip to move to southern Gaza along the main highway, the Salah al-Din Street.