President Joe Biden spoke with Israel’s Prime Minister Benjamin Netanyahu on Monday afternoon, once again addressing his commitment to efforts to “secure the release of all remaining hostages taken by Hamas – including Americans – and to provide for safe passage for U.S. citizens and other civilians in Gaza,” according to a White House readout of the call. Biden welcomed the news of the two hostages who were released earlier on Monday, per the readout.

During the call, Biden also “underscored the need to sustain a continuous flow of urgently needed humanitarian assistance into Gaza,” according to the readout.

Biden also spoke with Netanyahu about U.S. support for Israel and what the White House said was “ongoing efforts at regional deterrence, to include new U.S. military deployments.”

-ABC News’ Ben Gittleson

White House National Security Council spokesman John Kirby said Monday that in recent days there had been "an uptick in rocket and drone attacks by Iranian-backed proxy groups against military bases housing U.S. personnel in Iraq and Syria."

“We know Iran continues to support Hamas and Hezbollah, and we know Iran is closely monitoring these events and in some cases, actively facilitating attacks and spurring on others who may want to exploit for their own good, or for that of Iran," Kirby said.

Kirby said Iran tries to "maintain some level of deniability here, but we’re not going to allow them to do that."

He added that there is still no direct evidence that Iran was involved in Hamas' Oct. 7 terrorist attack on Israel.

-ABC News' Ben Gittleson

Two hostages have been released by Hamas, the Israeli Hostage Center confirmed.

The hostages are two elderly women who are both Israeli nationals, the center said. The released hostages are 85-year-old Yocheved Lifshitz and 79-year-old Nurit Cooper, both from the Nir Oz kibbutz, the center said.

The Red Cross said it helped transport the hostages out of Gaza Monday evening. The hostages have since arrived back in Israel, the hostage center said.

The Israeli military said Monday that at least 222 hostages were taken by Hamas since Oct. 7. Two American hostages, a mother and daughter, were released on Friday.

The Family Forum of the Missing and Hostages said in a statement, "Over 200 Israeli citizens are being held in deplorable conditions and have been waiting to return home for 17 days. We call on the Israeli government and world leaders to bring everyone home now."

President Joe Biden was asked by a reporter Monday if the U.S. is supporting a deal for hostages in exchange for a cease-fire.

Biden replied, "We should get -- we should have a cease-fire -- not a cease-fire -- we should have those hostages released, and then we can talk."

-ABC News' Ben Gittleson

At least 500 people have been killed in an explosion at Al Ahli Arab Hospital in the middle of Gaza, according to the Gaza Health Ministry.

The hospital served as a shelter for thousands of residents who fled their homes in northern Gaza.

The Israel Defense Forces denied responsibility for the explosion, saying a failed launch by the Palestinian Islamic Jihad caused the blast.

"From the analysis of the operational systems of the IDF, an enemy rocket barrage was carried out towards Israel, which passed in the vicinity of the hospital, when it was hit," IDF said.

The World Health Organization condemned the blast and called for "the immediate active protection of civilians and health care" workers.

This hospital "was one of 20 in the north of the Gaza Strip facing evacuation orders from the Israeli military," the WHO said in a statement. "The order for evacuation has been impossible to carry out given the current insecurity, critical condition of many patients, and lack of ambulances, staff, health system bed capacity, and alternative shelter for those displaced."

Palestinian Authority President Mahmoud Abbas has declared three days of mourning following the attack.

-ABC News' Will Gretsky