The co-founder and Board chair of Horizon Maritime, the company that owns the Polar Prince boat that took the Titan submersible out to sea, is speaking out.

"We have been supporting the Titanic expeditions for several years," Sean Leet said, calling the Polar Prince "an iconic former Canadian Coast Guard icebreaker that has been upgraded with advanced technology."

"All protocols were followed" for the submersible's mission, he said at a news conference Wednesday, calling the missing sub an "unprecedented" situation.

Equipment heading to search site can reach the depths of the submersible and potentially take it to the surface, he said.

"We wish to thank everyone involved in this rescue mission, especially the U.S. and Canadian Coast Guards, the organizations that have made their marina assets available including the French government … [and] the many private companies that have dropped everything at a moment's notice," Leet said.

"Our thoughts and focus remain with the crew of the Titan and their families," he said.

Leet said he is holding out hope that the five-person crew will be brought home safely.

"We'll continue to hold out hope until the very end," he said.

As crews scour the Atlantic Ocean for the missing submersible, the U.S. Coast Guard said it's searching in the area where underwater noise was detected.

The unidentified noise was detected Tuesday night and Wednesday morning.

The data on the noise was sent to the U.S. Navy to be examined, according to the Coast Guard.

"We have to remain optimistic and hopeful when we're in a search and rescue mission," Capt. Jamie Frederick, the First Coast Guard District response coordinator, said at a press conference on Wednesday afternoon.

The deep-sea vessel submerged on Sunday morning with five people aboard and a 96-hour oxygen supply, according to the Coast Guard. That amount of breathable air is forecast to run out on Thursday morning.

When asked about the search becoming a recovery mission, Frederick told reporters: "We're not there yet."

One of the ships the Canadian Coast Guard sent to the rescue effort, the John Cabot, is equipped with advanced, deep sonar, said Joyce Murray, minister of Fisheries, Oceans and the Canadian Coast Guard.

"We've sent so many assets to the search team to help," Murray said. "Authorities still have hope in the mission."

-ABC News' Will Gretsky

Mike Reiss, who has done four, 10-hour dives with OceanGate, including one to the Titanic, told ABC News his sub lost contact with the host ship on every dive.

"Every time they lost communication -- that seems to be just something baked into the system," he said.

With no GPS, Reiss said it took his crew three hours to find the Titanic despite landing just 500 yards from the ship.

Reiss said he signed "a waiver that mentions death three times on the first page.”

"It is always in the back of your head that this is dangerous, and any small problem will turn into a major catastrophe," he said.

He said the submersible is built simply and is "just propelled by two fans on the outside."

"Even I was able to steer and navigate the sub for a while," he noted.

Reiss said his greatest fear was that the sub wouldn’t be able to release the weights that force it to submerge once it was time to rise to the surface.

-ABC News' Gio Benitez and Sam Sweeney

Samad Dawood, the brother of Shahzada Dawood, one of the passengers who died in the submersible, said losing his brother and nephew, Suleman Dawood, is heartbreaking.

"This is beyond what you could ever imagine in terms of the kind of hardships and struggle that we've had. I think what we've seen is enormous tragedy and devastation and a lot of emotions. Obviously we were hoping to hear some good news about the rescue and them coming back. It was heartbreaking to find out that that's not the case," Samad Dawood told ABC News.

Samad Dawood said his brother had a strong sense of adventure and curiosity about the world.

"He was always the kind of person who has this incredible love for the world," Samad Dawood said.

"He inspired us curiosity. And he was a guy who just wanted to go out there, experience what the world had to offer, even though he he himself pushed himself to do it. So they made adventures to go to Antarctica, to go to Greenland and to go to Africa and go to the rapids," Samad Dawood said.

This sense of adventure was passed on to Shahzada Dawood's son, 19-year-old Suleman Dawood, who was also in the submersible. Suleman Dawood had traveled to all seven continents, according to Samad Dawood.

"He was so filled with humbleness and gratitude," Samad Dawood said.

"We're deeply grateful for all the support and the love and the effort that the people have made, working tireless nights being optimistic in giving a sense of hope, giving that transparency to us. But obviously we were devastated as a family ... that we couldn't get them back safe," Samad Dawood said.

-ABC News' Octavio Cadenas, Dr. Jennifer Ashton and Victor Ordonez