The co-founder and Board chair of Horizon Maritime, the company that owns the Polar Prince boat that took the Titan submersible out to sea, is speaking out.

"We have been supporting the Titanic expeditions for several years," Sean Leet said, calling the Polar Prince "an iconic former Canadian Coast Guard icebreaker that has been upgraded with advanced technology."

"All protocols were followed" for the submersible's mission, he said at a news conference Wednesday, calling the missing sub an "unprecedented" situation.

Equipment heading to search site can reach the depths of the submersible and potentially take it to the surface, he said.

"We wish to thank everyone involved in this rescue mission, especially the U.S. and Canadian Coast Guards, the organizations that have made their marina assets available including the French government … [and] the many private companies that have dropped everything at a moment's notice," Leet said.

"Our thoughts and focus remain with the crew of the Titan and their families," he said.

Leet said he is holding out hope that the five-person crew will be brought home safely.

"We'll continue to hold out hope until the very end," he said.

As crews scour the Atlantic Ocean for the missing submersible, the U.S. Coast Guard said it's searching in the area where underwater noise was detected.

The unidentified noise was detected Tuesday night and Wednesday morning.

The data on the noise was sent to the U.S. Navy to be examined, according to the Coast Guard.

"We have to remain optimistic and hopeful when we're in a search and rescue mission," Capt. Jamie Frederick, the First Coast Guard District response coordinator, said at a press conference on Wednesday afternoon.

The deep-sea vessel submerged on Sunday morning with five people aboard and a 96-hour oxygen supply, according to the Coast Guard. That amount of breathable air is forecast to run out on Thursday morning.

When asked about the search becoming a recovery mission, Frederick told reporters: "We're not there yet."

One of the ships the Canadian Coast Guard sent to the rescue effort, the John Cabot, is equipped with advanced, deep sonar, said Joyce Murray, minister of Fisheries, Oceans and the Canadian Coast Guard.

"We've sent so many assets to the search team to help," Murray said. "Authorities still have hope in the mission."

-ABC News' Will Gretsky

Mike Reiss, who has done four, 10-hour dives with OceanGate, including one to the Titanic, told ABC News his sub lost contact with the host ship on every dive.

"Every time they lost communication -- that seems to be just something baked into the system," he said.

With no GPS, Reiss said it took his crew three hours to find the Titanic despite landing just 500 yards from the ship.

Reiss said he signed "a waiver that mentions death three times on the first page.”

"It is always in the back of your head that this is dangerous, and any small problem will turn into a major catastrophe," he said.

He said the submersible is built simply and is "just propelled by two fans on the outside."

"Even I was able to steer and navigate the sub for a while," he noted.

Reiss said his greatest fear was that the sub wouldn’t be able to release the weights that force it to submerge once it was time to rise to the surface.

-ABC News' Gio Benitez and Sam Sweeney

The United States Coast Guard commander leading the search for a missing submersible off the coast of Newfoundland, Canada, said Tuesday morning that crews in multiple aircraft have flown over an area of the Atlantic Ocean "roughly about the size of Connecticut" while "looking for any signs of surfacing."

"As we continue on with the search, we're expanding our capabilities to be able to search under the water as well," Rear Adm. John Mauger, commander of the First Coast Guard District, told ABC News' Robin Roberts during an interview on "Good Morning America."

A commercial vessel with remotely operated vehicles is now on scene that will allow rescuers to search underwater, according to Mauger.

"This is a complex case," he added. "The Coast Guard doesn't have all the resources to be able to affect this kind of rescue, although this is an area that's within our search zone."

In many cases, Mauger said, the Coast Guard's role is to coordinate all of the assets and technical expertise that can be used in a search, in addition to operating aircraft or ships when necessary.

"In this particular case, we've established a unified command with the United States Navy, with the Canadian Armed Forces, with the Canadian Coast Guard and with the private operator OceanGate Expeditions to make sure that we understand what's needed and deploy all available equipment to the scene that could be used to locate this submersible, whether it's on the surface or down beneath the surface," he said.

Crews have been working "around the clock" to locate the deep-sea vessel since it lost contact with its operator on Sunday morning, according to Mauger.

In the last 24 hours, a Canadian aircraft has been dropping sonar buoys into the water that can pick up sound the submersible may be emitting. Vessels that have the capability to listen with their own sonar equipment are also on scene, according to Mauger.

"If they are making sound, that's certainly one of the ways that we're going to use to locate them," he said.