NASA released a statement Tuesday on the Titan, saying it remains "hopeful the crew will be found unharmed."

"NASA’s Marshall Space Flight Center had a Space Act Agreement with OceanGate, and consulted on materials and manufacturing processes for the submersible. NASA did not conduct testing and manufacturing via its workforce or facilities," the agency said.

-ABC News' Gina Sunseri

The U.S. Navy said it's sending to the search site experts and equipment "designed to provide reliable deep ocean lifting capacity for the recovery of large, bulky, and heavy undersea objects."

The equipment, which can lift up to 60,000 pounds, and the experts will arrive in Canada Tuesday night, the Navy said.

National Security Council spokesperson John Kirby said earlier Tuesday that the Navy was"on standby" to help with the search for the missing submersible, because the Navy has "some deep-water capabilities that the Coast Guard wouldn’t necessarily have."

President Joe Biden is "watching events closely," Kirby said, adding that Biden and the White House offer their thoughts "to the crew onboard, as well as to the -- what is no doubt -- worried family members back on shore."

Three U.S. Air Force C-17 cargo aircraft will be transporting commercial equipment from Buffalo, New York, to Newfoundland, Canada, to help with the search efforts, according to a U.S. official.

-ABC News' Luis Martinez

Efforts to locate the missing submersible are ongoing, and the "complex" search covers an area larger than the state of Connecticut, Coast Guard Capt. Jamie Frederick said at a news conference Tuesday.

Crews are scouring the ocean 900 miles east of Cape Cod and 400 miles south of St. John's, Canada, he said.

The missing five-person crew on the submersible has about 41 hours of oxygen left, Frederick noted.

"We will do everything in our power to effect a rescue," Frederick said.

"We have a group of our nation's best experts," he said, and once the sub is located, "those experts will be looking at what the next course of action is" to rescue the crew members.

"Our thoughts and prayers are with the crew and their families and their loved ones," Frederick added.

Digital marketing tycoon Chris Brown originally planned to go on Sunday's submersible tour of the Titanic wreckage but withdrew due to safety concerns. His friend, Hamish Harding, is among those aboard the missing vessel.

Brown, who described himself as a "modern day adventurer," admitted that he knew "very little" about the tour operator, OceanGate Expeditions, prior to signing up. But he said the deep-sea trip initially sounded "like a great idea."

"The Titanic's obviously an iconic wreck," Brown told ABC News' Michael Strahan during an interview Wednesday on "Good Morning America."

"OceanGate had put forward this program to go down and do a 3D scan of the wreck," he added. "So it's a chance for an expedition, exploration and adding a bit of science into the situation."

Brown said safety concerns ultimately led him to pull out of the trip, but he declined to go into detail.

"I'm not really sure that this is the time to be going into that sort of thing," he added. "I think that the focus right now has to be on trying to rescue these people. It's not fair on the families and friends to be making speculation about what might've happened or how it happened at this point."

Brown said he feels "no" apprehension about joining similar projects in the future but noted that it's important to "think about all the risks."

"If you don’t have an appetite for those risks, then you might not go ahead," he said. "You may try and mitigate those by bringing in some expertise from outside. You might have other risks or dangers that could be mitigated by changing the time of when you go out there."