Biden, in an evening address from Wilmington, Delaware, is announcing his vaccination and economic rescue legislative package.

The ambitious $1.9 trillion proposal focuses on stimulus amid the ongoing pandemic.

Biden's plan would dedicate more than $1 trillion of the $1.9 trillion price tag for direct stimulus, officials said, while $400 billion would go toward COVID-related projects, including the nationwide vaccination program, and $440 billion toward relief for communities and businesses.

The plan includes direct payments of up to $1,400 to families in need, that when combined with the recent $600 stimulus payment would deliver on Biden's pledge to pass $2,000 of direct payments, along with a $400 weekly unemployment insurance benefit through September and a child tax credit.

-ABC News' Molly Nagle

Photos show the beginning of the process to move President Donald Trump out of the White House, as workers load boxes on to trucks.

Biden on Thursday announced his slate for new leadership at the Democratic National Committee, including former South Carolina U.S. Senate candidate Jaime Harrison to be the next chair of the DNC.

Harrison, who lost the 2020 race to GOP Sen. Lindsey Graham last year, despite breaking numerous fundraising records, will officially become DNC chair after the full committee votes on Jan. 21, the day after Biden's inauguration.

Graham congratulated Harrison on the news in a tweet earlier Thursday.

In addition to Harrison, Biden also announced the names of four DNC vice chairs, all of whom were prominent backers of his presidential campaign, including Michigan Gov. Gretchen Whitmer, who served as a campaign co-chair.

Whitmer is joined by Atlanta Mayor Keisha Lance Bottoms, Illinois Sen. Tammy Duckworth and Texas Rep. Filemon Vela as new DNC vice chairs.

House Speaker Nancy Pelosi called Harrison an "inspiring, energizing and influential" in a press release.

"As former Chair of the South Carolina Democratic Party and senatorial candidate, Jaime brings an outstanding track record of success -- from galvanizing the grassroots, mobilizing millions and shattering fundraising records -- that will be critical during this pivotal moment for our Party and Country," she added.

-ABC News' John Verhovek and Beatrice Peterson

During an unscheduled stop on Capitol Hill, Vice President Mike Pence greeted National Guardsmen and telling them that he had just come from a briefing where he heard about their efforts.

He thanked the personnel for "stepping forward for your country" to make the historic transfer of power possible.

"It's been my great honor to serve as your vice president and I want to thank you for your service," Pence said.

The vice president then spoke to individual guardsmen asking them where they are from and how long they served.

About 20,000 National Guard members are expected in Washington this week to protect the city ahead of Biden's inauguration.

"Have a safe inauguration," Pence said.

-ABC News' Elizabeth Thomas and John Parkinson

Biden outlined the major points of his rescue plan: a $1.9 trillion proposal that includes a nationwide vaccination program, $1,400 checks for individuals, an extension and expansion of unemployment benefits and help for struggling communities and businesses.

Biden placed particular emphasis on housing and food insecurity and spoke about expanding SNAP benefits. He said his policy plan would extend the eviction and foreclosure moratorium, potentially previewing an executive action we could see next week. He also asked Congress to appropriate funds for rental assistance.

Biden, who preached bipartisanship while on the trail, said both he and Vice President-elect Harris had spoken with officials, mayors, and governors of both parties on a regular basis to address the problems across the country.

The president-elect also emphasized his plan's focus on helping small businesses and minority-owned businesses in particular, criticizing the Trump administration's initial approach which he said favored the wealthy and well-connected.

"Last week, I laid out how we'll make sure that our emergency small business relief is distributed swiftly and equitably, unlike the first time around. We're going to focus on small businesses, on Main Street. We'll focus on minority-owned small businesses, women-owned small businesses, and finally having equal access to the resources they need to reopen and to rebuild," Biden said.

He also pushed his plan for a mandatory federal minimum wage of $15 an hour.

"People tell me that's going to be hard to pass. Florida just passed it, as divided as that state is, they just passed it. The rest of the country is ready to move as well," he said. "No one working 40 hours a week should live below the poverty line. And that's what it means. If you work for less than $15 an hour and work 40 hours a week, you're living in poverty."

He frankly noted the "bold, practical" policy he was putting forward did not come cheap but argued there was no option to act.

"I know what I just described does not come cheaply. But failure to do so will cost us dearly," he said. "The consensus among leading economists is we simply cannot afford not to do what I'm proposing."

Biden ended his remarks with a call for unity and optimism, referencing his inauguration on Wednesday as a "new chapter for the country."

-ABC News' John Verhovek, Molly Nagle, Averi Harper and Beatrice Peterson