Perdue's campaign team released a statement early Wednesday, saying the race is "exceptionally close" but that they believe the incumbent Republican senator "will be victorious."

"As we've said repeatedly over the last several weeks and as recently as this evening, this is an exceptionally close election that will require time and transparency to be certain the results are fair and accurate and the voices of Georgians are heard," the Perdue campaign said. "We will mobilize every available resource and exhaust every legal recourse to ensure all legally cast ballots are properly counted. We believe in the end, Senator Perdue will be victorious."

The race between Perdue and his Democratic challenger, Ossoff, is too close to call as votes are still being tallied.

-ABC News' Quinn Scanlan

Ossoff’s campaign manager, Ellen Foster, released a statement early Wednesday saying that when all the votes are counted, their team "fully" expects Ossoff will win his Senate runoff against Perdue.

"The outstanding vote is squarely in parts of the state where Jon’s performance has been dominant," Foster said. "We look forward to seeing the process through in the coming hours and moving ahead so Jon can start fighting for all Georgians in the U.S. Senate."

If Democrats win both Senate seats in Georgia, each party will have 50 senators, and Vice President-elect Kamala Harris will be the tie-breaking vote for Democrats in the Senate.

-ABC News' Quinn Scanlan

Warnock, a prominent Black preacher who leads the storied Ebenezer Baptist Church, secured a barrier-breaking victory in Georgia on Tuesday night.

The native-born son, who delivers sermons from the pulpit that once belonged to the Rev. Dr. Martin Luther King Jr., will become the first Black senator from Georgia -- a feat that closes out an election cycle dominated by the role of race in politics.

He is only the second Black senator elected from the south since Reconstruction, and among a rare class of 10 Black Americans who have served in the upper chamber.

ABC News projected just before 2 a.m. that Warnock will topple Loeffler, a prominent Republican donor and staunch ally of President Trump who earned political office after being appointed by Gov. Brian Kemp to the seat.

In the remaining Georgia Senate race between Ossoff and Perdue, there is less than 1% separating the two candidates and so, the race is too close to project.

-ABC News' Kendall Karson

Up by roughly 35,000 votes statewide, Warnock declared victory in Georgia with a virtual speech to supporters in the early hours of Wednesday morning.

"The other day, because this is America, the 82-year-old hands that used to pick somebody else's cotton went to the polls and picked her youngest son to be a United States senator,” Warnock said.

ABC News has not made a projection on the race, but if Warnock wins, the native-born son, who delivers sermons from the pulpit that once belonged to the Rev. Dr. Martin Luther King Jr., will become the first Black senator from Georgia.

“So I come before you tonight as a man who knows that the improbable journey that led me to this place in the historic moment in America could only happen here,” Warnock continued. “May my story be an inspiration to some young person who is trying to grasp and grab hold of the American dream.”

Taking a page from President-elect Joe Biden's playbook, Warnock went on to say he'd be a senator for those who didn't vote for him as much as for those who did support him.

“To everyone out there struggling today, whether you voted for me or not, know this, I hear you, I see you. And every day I'm in the United States Senate, I will fight for you,” he said.

President-elect Joe Biden said that he feels "optimistic" about Tuesday's pivotal runoff elections in Georgia during an interview on V103 with Kenny Burns, a local Atlanta radio host.

"I'm doing really well, feeling really optimistic about today," Biden told Burns.

Asked what specific policies he expects to come before the Senate this year that make it so critical for Democrats Jon Ossoff and Rev. Raphael Warnock to win, Biden cited both the need to get $2,000 payments to struggling Americans and harshly criticized the federal government’s vaccine distribution plan at length, saying Congress needs to be able to provide support to get the vaccine out to all Americans.

"Right now, for example in Georgia, you have only about 75,000 people who have gotten the vaccination, yet you got about a half a million doses of that vaccine in the state. There's no planning. The federal government has done virtually no planning. It's one thing to get a vaccination -- to get to get the actual vial -- sent to you in a frozen pack. It's another thing to get it into a needle and the vaccination into somebody’s arm," Biden said.

"So I'm gonna need [Congress'] help in making sure that we establish thousands of federally-run and federally-supported community vaccination centers of various sizes across the country. Located in high school gyms or NFL football stadiums," Biden said, adding that the vaccination project has to involve multiple levels of the government including FEMA and the under his administration vaccines will be free.

"The inability of the president and the Republican leadership, and Trump in particular, preventing that from being made available to the states is just -- it's just almost criminal in my view. And people are dying,” Biden later added.

The president-elect once again hammered Georgia’s two Republican senators and candidates, Kelly Loeffler and David Perdue, saying they’ve forgotten who they have been elected to represent.

"Look here's the thing that's happening. Because of the Republican senators of Georgia, their loyalty is to Trump, not to the people of Georgia. I mean, when I got sworn into the Senate I didn't swear allegiance to the president, whether it was a Democrat or Republican. I'm not going to have any senators swear allegiance to me. It's to the Constitution and to the state of Georgia, that's who you represent," Biden said.

-ABC News' John Verhovek, Beatrice Peterson and Molly Nagle