Senate Republicans are overwhelmingly admonishing their House colleagues for allowing McCarthy's speakership to be vacated, calling it a "sad day."

Sen. John Cornyn of Texas said ousting McCarthy was a "disgraceful" move by a small group of House conservatives.

"These insurgents have no plan," Cornyn said. "And now they've created even more chaos and it's not good for the House, it's not good for Republicans," he said.

A visibly miffed Sen. Roger Wicker of Mississippi agreed: "It stinks, and it's bad for the country."

Republicans are the minority party in the Senate. With a much more favorable map on the horizon in 2024, some now worry the dysfunction in the House will be a distraction for voters.

-ABC News' Allison Pecorin

The White House confirmed late Tuesday afternoon that President Joe Biden saw the developments in the House, but the administration is declining to weigh in on congressional politics.

Instead, aides said Biden is focused on governing and they pointed to the announcement earlier Tuesday on drugmakers agreeing to take part in Medicare negotiations.

-ABC News' Justin Gomez

McCarthy exited the chamber declining to comment after the House voted to remove him.

Several members in GOP leadership are currently meeting inside McCarthy's office. Republicans are slated to gather behind closed doors on Tuesday evening for a conference meeting.

McCarthy shook his head slightly when the presiding officer slammed the gavel after the roll call vote.

Gaetz spoke to reporters outside the Capitol just moments after his motion to vacate succeeded.

"The stages of grief are in progress," he said.

The Florida Republican floated names for who could become the next speaker. On his list were House Majority Leader Steve Scalise, House Majority Whip Tom Emmer and Oklahoma Rep. Kevin Hern.

Gaetz said he will "absolutely not" put himself forward for speakership.

Debate began Tuesday afternoon on the motion to vacate ahead of the vote on it. Gaetz ceded the floor to Virginia Republican Rep. Bob Good.

"Like so many others, I deeply regret that we are here in a totally avoidable situation," Good said as he began his remarks, which largely targeted McCarthy's actions on spending to date. "I must take you back to January, however, which for many of us was about not repeating the failures of the past and letting Republican voters across the country down once again."

Good continued, "Back in January, I expressed my concern that the previous two years during my first term here in this House, we had not used every tool at our disposal to fight against the harmful, radical, Democratic agenda that is destroying the country, bankrupting the country and under which the American people are suffering."