Senate Republicans are overwhelmingly admonishing their House colleagues for allowing McCarthy's speakership to be vacated, calling it a "sad day."

Sen. John Cornyn of Texas said ousting McCarthy was a "disgraceful" move by a small group of House conservatives.

"These insurgents have no plan," Cornyn said. "And now they've created even more chaos and it's not good for the House, it's not good for Republicans," he said.

A visibly miffed Sen. Roger Wicker of Mississippi agreed: "It stinks, and it's bad for the country."

Republicans are the minority party in the Senate. With a much more favorable map on the horizon in 2024, some now worry the dysfunction in the House will be a distraction for voters.

-ABC News' Allison Pecorin

The White House confirmed late Tuesday afternoon that President Joe Biden saw the developments in the House, but the administration is declining to weigh in on congressional politics.

Instead, aides said Biden is focused on governing and they pointed to the announcement earlier Tuesday on drugmakers agreeing to take part in Medicare negotiations.

-ABC News' Justin Gomez

McCarthy exited the chamber declining to comment after the House voted to remove him.

Several members in GOP leadership are currently meeting inside McCarthy's office. Republicans are slated to gather behind closed doors on Tuesday evening for a conference meeting.

McCarthy shook his head slightly when the presiding officer slammed the gavel after the roll call vote.

Gaetz spoke to reporters outside the Capitol just moments after his motion to vacate succeeded.

"The stages of grief are in progress," he said.

The Florida Republican floated names for who could become the next speaker. On his list were House Majority Leader Steve Scalise, House Majority Whip Tom Emmer and Oklahoma Rep. Kevin Hern.

Gaetz said he will "absolutely not" put himself forward for speakership.

After Rep. Bob Good, R-Va., delivered a speech castigating McCarthy and explaining why he was joining Gaetz in the motion to vacate, Republican Rep. Tom Cole of Oklahoma spoke out in support of McCarthy and warned of "chaos" should the conference's breakaway faction succeed in removing him.

"They're willing to plunge this body into chaos, and this country into uncertainty, for reasons only they understand," Cole said. To the Democrats who are expected to vote against McCarthy as well, Cole said, "Think long and hard before you plunge us into chaos."

Cole also celebrated how McCarthy had navigated the differences in the closely divided House -- and Washington more broadly -- to notch spending cuts in the debt limit fight earlier this year, pushing back on criticism from Gaetz and others that McCarthy hadn't done enough to curb the federal budget.

Cole also suggested McCarthy had proven himself capable of making sure the House would continue to accomplish Republican priorities.

"I'm very proud of this speaker. I'm very proud to stand behind him. Tomorrow morning, whether I win or lose, I'm going to be pretty proud of the people I fought with and I'm going to be pretty proud of the person I fought for," Cole said.

-ABC News' Adam Carlson