Sarah Huckabee Sanders, delivering the Republican response to the State of the Union, offered a bleak picture of Biden's presidency.

"In the radical left's America, Washington taxes you and lights your hard-earned money on fire but you get crushed with high gas prices, empty grocery shelves and our children are taught to hate one another on account of their race but not to love one another or our great country," she said. "Whether Joe Biden believes this madness or is simply too weak to resist it, his administration has been completely hijacked by the radical left."

Sanders called Biden "unfit to serve" as she criticized his handling of the southern border, crime, the U.S. withdrawal from Afghanistan and more.

"Every day we are told we must partake in their rituals, salute their flags and worship their false idols," she said of Democrats. "All while big government colludes with big tech to strip away the most American thing there is: your freedom of speech. That's not normal. It's crazy. And it's wrong."

The opposition response to the State of the Union has been around for more than half a century, but in modern times the opposition party has often used it to showcase a new, high-profile figure. It's no different this year, as Republicans were represented by Arkansas Gov. Sarah Huckabee Sanders, who served as a press secretary in the Trump White House.

Sanders just won her new office in November, making her the first woman governor in Arkansas's history. This puts her right at home with many first-term governors, senators and representatives who've given a response speech in recent years. Previous orators include Democratic Gov. Tim Kaine of Virginia in 2006, Republican Sen. Marco Rubio of Florida in 2013, Republican Sen. Joni Ernst of Iowa in 2015 and Democratic Gov. Gretchen Whitmer of Michigan in 2020.

And with the proliferation of response speeches in different languages and from various party factions, even more fresh faces are in the limelight this year. First-term GOP Rep. Juan Ciscomani of Arizona gave the Spanish-language response for his party, while first-term Democratic Rep. Delia Ramirez of Illinois offered the Working Families Party's response.

-FiveThirtyEight's Geoffrey Skelley

Arkansas Gov. Sarah Huckabee Sanders delivered the Republican response to President Biden's State of the Union, in which he called on Congress to "finish the job" on health care, the economy, policing and more.

"Being a mom to three young children taught me not to believe every story I hear. So, forgive me for not believing much of anything I heard tonight from President Biden. From out-of-control inflation and violent crime to the dangerous border crisis and threat from China, Biden and the Democrats have failed you," Sanders said.

She quickly drew on some key differences between her and Biden, saying they "don't have a lot in common."

"At 40, I'm the youngest governor in the country. At 80, he's the oldest president in American history," she said. "I'm the first woman to lead my state. He's the first man to surrender his presidency to a woke mob that can't even tell you what a woman is."

While he didn't directly mention it, Biden made a passing reference to what the federal government said was a Chinese surveillance balloon that flew for days over the continental U.S. before being shot down by the military on Saturday.

"I'm committed to work with China where we can advance American interests and benefit the world," Biden said as he spoke briefly about foreign policy. "But make no mistake about it, as we made clear last week, if China threatens our sovereignty, we will act to protect our country and we did."

Biden argued that "winning the competition with China should unite all of us."

Senate Minority Leader Mitch McConnell slammed Joe Biden for what he called the nation’s economic woes under two years of Democratic control -- just hours ahead of the president’s State of the Union address.

The Kentucky Republican appeared to rely heavily on new ABC News/Washington Post polling -- while not citing the data directly -- in remarks on the Senate floor, claiming Biden has created an America in which only 16% of citizens feel they are in a better financial situation than they were in two years ago.

"For 84 percent of Americans, one party Democratic control of Washington either failed to live up to its consequences or actively made life worse,” McConnell said.

McConnell hit Biden on inflation, immigration, the Afghanistan withdrawal, school choice, and more in the lead up to Biden's speech tonight.

He also criticized the administration for its handling of the Chinese spy balloon, arguing that it was "ludicrous to suggest that Canada and the United States had no choice but to let this thing traipse across the continent from coast to coast. "

–ABC News’ Allie Pecorin