Obama, Raul Castro to Come Face-to-Face as White House Hints at Historic Encounter Between US, Cuban Leaders

The two leaders will attend the Summit of the Americas in Panama.

Rhodes said that while no formal meeting is scheduled, it’s likely the two will interact on the sidelines of the event. It’s still unclear whether any interaction or meeting between the two leaders will be caught on camera.

The Seventh Summit of the Americas will take place Friday and Saturday in Panama City. This will be the first time Cuba will attend the summit.

“That in its own right is an important step forward in our view,” Rhodes said, adding that it was not “constructive” for the United States to prevent Cuba from attending.

This is also the first time all 35 countries in the Western hemisphere will attend the summit.

ABC News' Mary Bruce contributed to this report.