Biggest NFL injuries of Week 5

— -- Here are the most significant NFL players who got banged up in Week 5:

Cody Kessler, QB, Cleveland Browns:?Kessler landed hard on his throwing shoulder after getting hit by Patriots LB Dont'a Hightower in the first quarter. He went to the locker room for further evaluation and was eventually ruled out with with chest/rib injuries.? Charlie Whitehurst replaced Kessler in the starting lineup. WR Terrelle Pryor has also seen some time at QB this season.

Eddie Lacy, RB, Green Bay Packers:?Giants linebacker Jacquian Williams hit Lacy's left ankle hard in the third quarter Sunday night. He did not return to the game and finished with 81 yards on 11 carries.

Jeremy Hill, RB, Cincinnati Bengals: Hill entered this week with a chest injury, and the team announced that he hurt his chest again Sunday. He did not return to the field. Hill appeared to sustain the injury after getting stuffed for a 1-yard loss in the third quarter.

Trumaine Johnson, CB, Los Angeles Rams: Johnson entered this week in a tie for the league lead in pass breakups. He had his right ankle rolled up on in the fourth quarter Sunday and couldn't put any weight on his leg as he left the field. He was carted to the locker room, and after the game, he was wearing a protective boot and on crutches.

Steve Smith Sr., WR, Baltimore Ravens: Smith hobbled off the field in the first quarter because of an ankle injury. After getting it retaped and testing it on the sideline, Smith went to the locker room. The team eventually ruled him out for the remainder of the game.

Josh Norman, CB, Washington Redskins:?Norman stayed on the ground for a while?after he landed hard on his right arm in the first quarter. He was able to walk off the field under his own power.?Norman missed a few series but returned to the field in the second quarter. The team officially called it a right wrist injury.

Cameron Heyward, DE, Pittsburgh Steelers:?Heyward went to the locker room in the second quarter with a hamstring injury and was eventually ruled out for the game. Heyward leads the Steelers with three sacks, all of which came last week against the Chiefs.

David Harris, LB, New York Jets:?Harris hurt his hamstring just before halftime against the Steelers. He limped off the field, and the team said he was doubtful to return. Harris entered this week second on the Jets with 19 tackles.

Eli Apple and Dominique Rodgers-Cromartie, CBs, New York Giants:?Apple (hamstring) and Rodgers-Cromartie (groin) were on the injury report this week, and both left Sunday night's game in the first half because of groin injuries. Rodgers-Cromartie bounced in and out of the lineup, while Apple was ruled out.

Chris Ho gan, WR, New England Patriots: Hogan was on the wrong end of a big hit after gaining 2 yards on an end-around in the third quarter. The team listed him as questionable because of a head injury, but he returned to the field after missing a few possessions.

Nick Mangold, C, Jets: Mangold tried to play through a knee injury on Sunday, but he left the field for good midway through the third quarter.

C.J. Mosley, LB, Ravens:?Mosley injured his hamstring while attempting to return an interception for a touchdown. He fumbled the ball out of the end zone as he reached for the goal line and limped off the field as the Redskins regained possession. Mosley did not come back into the game.

Johnathan Joseph, CB, Houston Texans: Joseph sustained a concussion in the first half against the Vikings. The team ruled him out for the remainder of the game.?

Cordarrelle Patterson, WR/KR, Minnesota Vikings:?Patterson landed hard on his hip at the tail end of a 15-yard gain in the second quarter. Patterson missed some time, but he returned to the field in the second half and scored a touchdown.

Martellus Bennett, TE, New England Patriots:?Bennett injured his right ankle on the Patriots' opening drive of the game while run blocking. He ran off the field with a limp, and the team listed him as questionable to return. He didn't miss much time and scored three touchdowns in the game's first 33 minutes.?

Brandon Fusco, G, Minnesota Vikings:?Fusco sustained a concussion on the Vikings' first drive of the game and was ruled out. Zac Kerin replaced Fusco at right guard.

Charlie Whitehurst, QB, Browns:?Whitehurst, Kessler's backup who was forced into action, limped off the field late in the fourth quarter. He got hit by Jonathan Jones as he threw and hurt his left knee. The Browns listed Whitehurst as probable, and he came back in the game to run out the clock on the game's final possession.