Brazil and Portugal, two of the favorites to win the World Cup, are already into the knockout stage, but they'll have a chance to tune up for the second round in their final group matches on Friday.

In Group G, Brazil faces Cameroon, which needs to win and get a loss from Switzerland to qualify or a draw and better goal differential than the Swiss. Switzerland is facing off with Serbia. Serbia would need to win and get a loss by Cameroon or have a better goal differential. The Swiss just need a win or draw to advance alongside Brazil.

In the other set of games Friday, Portugal faces off with South Korea and Uruguay faces Ghana. Portugal may rest its top players, including Cristiano Ronaldo, so South Korea will be looking to take advantage and grab an upset win. Tottenham star Son Heung-min and South Korea need to win and get a loss from Ghana, or, if that game ends in a draw, beat Ghana in goal differential.

Uruguay, sitting on 1 point just like Korea, needs a similar situation. They'll need to beat Ghana and get a loss from South Korea, or beat Korea out on goal differential if the Portugal-South Korea match ends in a draw.

Here's the schedule for Friday, the final day of group play:

Japan stunned perennial contender Spain with two goals early in the second half to win 2-1 and take the top spot in Group E.

Spain, thanks to a blowout victory over Costa Rica in their first game, advanced on goal differential over Germany. Germany defeated Costa Rica 4-2 in the other game in the group. Costa Rica had a chance to advance, but likely needed to win since the team was so far behind on goal differential.

Japan won on goals by Ritsu Doan in the 48th minute and Ao Tanaka in the 51st minute. Tanaka's goal was initially disallowed due to being offside, but it was reviewed and then allowed.

Japan had made the round of 16 in alternating years the last six World Cups until this year, now going back to back in 2018 and 2022. Japan will play Croatia in the next round while Spain will play Morocco.

Germany has now failed to get out of the group stage in two straight World Cups after winning in 2014 and finishing in the top 4 four tournaments in a row.

The No. 2 team in the world, Belgium, is headed home after a scoreless draw against Croatia in the last match of Group F. Croatia advanced to the knockout stages with the draw.

Belgium had several opportunities to score in the second half, many from star Romelu Lukaku, but could not break through. Lukaku, who has been dealing with a hamstring injury, was subbed in at the half.

In the other game in Group F, Morocco defeated Canada, 2-1, to take the top spot in the group. Hakim Ziyech got the Moroccans on the board quickly in the 4th minute and Youssef En-Nesyri added a second goal in the 23rd minute. The only goal for Canada was actually an own goal by Morocco.

Canada, in its second World Cup ever, has still yet to win a match.

U.S. star forward Christian Pulisic said Thursday he is ready to return to his team for training and is still hoping to play in the team's knockout round game against the Netherlands on Saturday.

"I'm gonna go meet now with the team and the medical staff and make a decision on [training] today," Pulisic said at a press conference. "Just kind of see how I'm feeling. Take it day-by-day right now, but doing everything in my power to be able to be out there on the field Saturday."

Pulisic suffered a pelvic contusion when crashing into the Iranian goalkeeper after knocking in the eventual game-winning goal Tuesday. He was checked out by trainers and eventually returned to the pitch before being substituted out at halftime.

He was taken to the hospital for a brief stay before returning to the hotel to greet the team returning after the win.

He said in a post on social media from the hospital that he would play on Saturday, a sentiment he echoed to Fox reporter Jenny Taft Thursday morning when he told her he'd play. Officially, he is still listed as "day-to-day."

The U.S. faces the Netherlands in the round of 16 on Fox at 10 a.m. Saturday. A U.S. team hasn't advanced past the round of 16 since 2002 when they defeated Mexico in the first knockout game before losing to Germany in the quarterfinals.

U.S. national team coach Gregg Berhalter tried to keep the focus on Tuesday's game at a press conference as he faced questions about why the U.S. team's Twitter account removed the Islamic emblem from Iran's flag in a post Sunday. He also insisted his team had no knowledge of the post.

The U.S. soccer federation said it removed the logo to show support for those protesting in the country against authoritarian rule and its treatment of women.

Berhalter tried to keep the focus on the uniting power of sports and the World Cup, even as Iran called for the U.S. to be kicked out of the World Cup for altering its flag.

"Sport is something that should bring people together, bring countries together," Berhalter said. "When you look at the Olympics, to see all those countries competing at the same time, is a wonderful event. The World Cup is very similar, where people come from all around the world. Fans come from all around the world, and you get to compete on the field, as brothers, so sport does have the ability to do that."

U.S. captain Tyler Adams was criticized by an Iranian reporter for mispronouncing "Iran," which he apologized for, and he was questioned about discrimination in the U.S., saying it is everywhere but there has been progress. But he also deflected attention back to the game.

"Listen, we support Iran's people and Iran's team. But that being said, you know, we're laser focused on this match as they are as well," Adams, 23, told reporters. "We know how important this is for our progress of our team and what we want to do to prove to our country, you know, how hard we've been working. And we know they want to do exactly the same."

The U.S. must defeat Iran Tuesday to advance to the knockout stage of the tournament.

-ABC News' Karyn Rhodus