Roughly 180,000 people have been evacuated to Russia from Ukraine, including the Russian-controlled areas of Luhansk and Donetsk in the Donbas region, according to the Russian Defense Ministry.

"As many as 5,460 people, including 1,125 children, have been evacuated from dangerous zones in various regions of Ukraine, as well as the Luhansk and Donetsk people's republics, without participation of the Ukrainian side over the past 24 hours, Mikhail Mizintsev, head of the Russian National Defense Control Center, said Wednesday. "Over 179,000 people, including 45,436 children, in total have already been [evacuated] since the beginning of the special military operation."

Mizintsev said a total of 20,961 vehicles crossed the state border of the Russian Federation, including 867 over the past day.

Mizintsev said of the citizens who evacuated to Russia, 166 were from Turkey, 41 Ukraine, 11 Egypt, eight Italy, seven Azerbaijan, six Pakistan, five India, as well as Swedish, Moroccan, and Brazilian citizens.

The U.N. High Commissioner for Refugees (UNHCR) said earlier Wednesday it has tallied 2.15 million people that have been evacuated from Ukraine since the Russian invasion began on Feb. 24, with more than half going to Poland.

Russian forces have closed in further on Kharkiv, gaining about 20 kilometers, about 12 miles, since Tuesday, a senior U.S. defense official told reporters at a press briefing Wednesday.

"It's still heavy, heavy fighting there," the official said on Day 14 of the Russian invasion. However, the U.S. does not believe Russia has "taken the city by any means," the official added.

The U.S. has not seen any significant movement toward Kyiv or Chernihiv since Tuesday, and there is still no sign of an any immanent amphibious assault on Odessa, the official said.

In southeast Ukraine, Mariupol remains isolated. Ukrainians are putting up stiff resistance, while Russians continue to bombard the city, the official said.

Russia has about 90% of its available combat power still intact, the official said. It has now launched more than 710 missiles against Ukraine -- about half being launched from within Ukraine and half being launched from within Russia, the official said.

-ABC News' Matt Seyler

Russia is retaining a temporary ceasefire in humanitarian corridors in Ukraine, head of the Russian National Defense Control Center Col. Gen. Mikhail Mizintsev alleged on Wednesday.

Ten of the corridors were proposed by Moscow, while three were proposed by Kyiv, Mizintsev told reporters at a press briefing.

"Today, at exactly 10 a.m. local time, in accordance with agreements reached on 10 humanitarian corridors initiated by the Russian Federation and three more at the request of the Ukrainian side, the Russian Armed Forces introduced a temporary ceasefire, which is being strictly observed until now," Mizintsev said

No practical measures for the preparation of humanitarian convoys have been carried out so far, and no one has ever arrived at the humanitarian corridors that have been opened, Mizintsev said. The formation of organized humanitarian convoys has also not been recorded, he claimed.

A devastating Russian airstrike has destroyed a maternity and children’s hospital in the besieged Ukrainian city of Mariupol, according to Ukrainian officials.

Ukraine’s president Volodymyr Zelenskyy and local officials have posted videos on social media of what appears to be the devastated hospital, partly caved in and with walls blown out, the grounds littered with burnt-out vehicles.

ABC News is attempting to independently verify the attack.

Ukrainian authorities have said there are casualties and Zelenskyy wrote that there are children under the rubble.

Ukrainian officials have accused Russia of deliberately targeting the hospital.

Pavlo Kirilenko, the head of the Donetsk regional military administration, wrote on Facebook that a Russian aircraft targeted the hospital. Other officials have suggested there were multiple strikes.

Zelenskyy has called it an “atrocity” and called on the international community again to impose a "no-fly" zone.

"Direct strike of Russian troops at the maternity hospital. People, children are under the wreckage. Atrocity! How much longer will the world be an accomplice ignoring terror? Close the sky right now! Stop the killings! You have power but you seem to be losing humanity,” Zelenskyy tweeted.