Peterson had to be helped to the locker room after injuring his right leg in the third quarter of Sunday's game.
Peterson stayed down on the field after a 5-yard run with 3:32 left in the third quarter, and he hobbled off the field with the assistance of athletic trainers. After being examined on the sideline, he hopped through a field-level club at the team's new stadium toward the Vikings' locker room.
Upon arriving in the locker room, Peterson was quickly ruled out.
Peterson suffered a devastating left knee injury in 2011 -- tearing both his ACL and MCL ligaments -- only to bounce back and rush for 2,007 yards in the 2012 regular season.