Speaking at Salem State University during an event scheduled before the release of the report, Brady said he hopes to respond as soon as he has time to fully process the report and investigation.
"Are you that slow a reader?" sportscaster Jim Gray jokingly asked.
"My athletic career is better than my academic career," Brady joked back, noting, "[I] usually only read X's and O's. ... This was a bit longer."
Brady's demeanor was upbeat throughout, smiling frequently before the cheering crowd.
The investigation, led by attorney Ted Wells, stated it "is more than probable" that Brady "was at least generally aware of the inappropriate activities" involving the release of air from the Patriots' footballs.
And asked whether the controversy has detracted from the joy of winning the Super Bowl, Brady responded: "Absolutely not," prompting loud cheers from the audience.
Brady had been scheduled to speak at the Salem State University panel long before the report was released on Wednesday.
His agent, Don Yee, issued a statement earlier today slamming the findings as "a significant and terrible disappointment."
"Its omission of key facts and lines of inquiry suggest the investigators reached a conclusion first, and then determined so-called facts later," Yee said in the statement.