Responding to Russia's accusation that the U.S. was behind Wednesday's drone attack on the Kremlin, White House spokesperson John Kirby said it was a "ludicrous claim."

"There's a word that comes to mind that I'm obviously not -- not appropriate to using on national TV," Kirby said on CNN on Thursday.

"I will just tell you Mr. Peskov is lying, and I mean, that's obviously, it's a ludicrous claim," he added. "The United States had nothing to do with this. We don't even know exactly what happened here, Kaitlin. But I can assure you, the United States had no role in it whatsoever."

Kirby said the U.S. does not have any information on who is behind the strike but are "trying to learn more about this as best we can."

-ABC News' Justin Gomez

Russian President Vladimir Putin's spokesman accused the United States of being involved in the drone attack on the Kremlin on Wednesday.

"We understand well that the decision about such terror attacks are taken not in Kyiv, but in Washington," Dmitry Peskov told reporters in a briefing. "Often targets are determined not in Kyiv but in Washington. They don't Kyiv the right everytime in choosing the means. In Washington they also clearly understand that we know that."

He added, "Without question. Such decisions -- the determining of targets and means -- are all dictated to Kyiv from Washington."

Peskov said it was important that Washington understand the "danger" of such involvement in an attack.

-ABC News' Patrick Reevell

Russian forces launched a "complex air strike" with "drones and missiles" on Kyiv early Thursday morning, the Kyiv City Military Administration said on Telegram.

The air raid siren went off in Kyiv for three and a half hours during the attack, the Kyiv City Military Administration said.

There were no casualties or injuries from the strikes.

"According to preliminary information, all the missiles and UAVs were destroyed," the Kyiv City Military Administration added.

This was the third attack on the capitol in four days, the administration said.

-ABC News' Natalia Kushniir

The U.S. Embassy in Ukraine sent an alert to Americans on Wednesday warning of an "ongoing heightened threat of missile attacks," including in Kyiv.

"In light of the recent uptick in strikes across Ukraine and inflammatory rhetoric from Moscow, the Department of State cautions U.S. citizens of an ongoing heightened threat of missile attacks, including in Kyiv and Kyiv Oblast," the alert stated.

The U.S. Embassy urged U.S. citizens to follow guidance from local authorities and to observe air alarms and shelter appropriately.

At least 21 people were killed and 48 injured by shelling in the Kherson region on Wednesday, Ukrainian officials said, as the death toll continues to rise.

A railway station and market in the city of Kherson were hit in strikes, which occurred across the Kherson region in southern Ukraine, officials said.

"A railway station and a crossing, a house, a hardware store, a grocery supermarket, a gas station -- do you know what unites these places? The bloody trail that [Russia] leaves with its shells, killing civilians in Kherson and Kherson region," Ukrainian President Volodymyr Zelenskyy said on Twitter.

All the victims were civilians, Zelenskyy said.

An ambulance was also damaged in the strikes, according to Ukrainian Prosecutor General Andriy Kostin.

"No military objects here. Just civilians, including children," Kostin said on Twitter.

At least one person was killed and three injured in the strike on the railway station, officials previously said.