The first shots were fired at Just-In-Time Recreation, a bowling alley in Lewiston, Maine, formerly known as Sparetime.

"None of this seems real, but unfortunately it is," the owners of the bowling alley said in a statement. "We are devastated for our community and our staff. We lost some amazing and wholehearted people from our bowling family and community last night. There are no words to fix this or make it better. We are praying for everyone who has been affected by this horrific tragedy. We love you all and hold you close in our hearts."

Minutes after the massacre at the bowling alley, the mass shooting continued at the nearby Schemengees Bar & Grille Restaurant.

"My heart is crushed. I am at a loss for words. In a split second your world gets turn upside down for no good reason," a statement from Schemengees said. "We [lost] great people in this community. How can we make any sense of this. Sending out prayers to everyone."

Three people are in critical condition and five others are in stable condition on Thursday morning in the wake of Wednesday night's mass shooting, according to Dr. John Alexander, chief medical officer at Central Maine Health Care.

Two patients have been transported to other hospitals and two others have been discharged, he said.

Alexander praised the work of the hospital staffers who jumped in to help. He said about 100 off-duty team members volunteered.

-ABC News' Alex Faul

At 6:56 p.m. Wednesday, emergency dispatchers began to receive 911 calls detailing a male shooting at Just-In-Time Recreation, a bowling alley in Lewiston, Maine, formerly known as Sparetime, State Police Col. William Ross told reporters during a news conference.

At 7:08 p.m., law enforcement received reports of an active shooter inside the billiards room at the Schemengees Bar & Grille Restaurant in Lewiston, about 4 miles south of the bowling alley, Ross said.

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The FBI is offering SWAT teams to assist with the manhunt and is also making available behavioral scientists who can help assess how the suspect, Robert Card, might behave in the coming hours, multiple law enforcement officials told ABC News.

U.S. Marshals are also assisting in the search for card, sources said.

Agents from the Bureau of Alcohol, Tobacco, Firearms and Explosives are running down potential gun purchases by the suspect, sources said.

-ABC News' Pierre Thomas

The Lewiston Police Department has issued a shelter-in-place order for the city. Residents are urged to stay inside with their doors locked.

The FBI is sending in aviation units to help in the search for the gunman. New Hampshire police are putting up roadblocks to try to confine the gunman if he’s on the run.

Maine Gov. Janet Mills said in a statement, "I am aware of and have been briefed on the active shooter situation in Lewiston. I urge all people in the area to follow the direction of State and local enforcement."

New Hampshire Gov. Chris Sununu said New Hampshire "officials have been in touch with our counterparts in Maine to offer and provide any medical and safety resources needed as they manage this horrific situation. Our hearts and prayers are with the people of Maine."

President Joe Biden spoke on the phone with Gov. Mills, Maine Sens. Angus King and Susan Collins and Rep. Jared Golden, D-Maine, and "offered full federal support in the wake of this horrific attack," according to the White House.