Calls to poison centers for fentanyl exposures in kids increased nearly 54-fold since 2016.

Seattle Mayor Bruce Harrell says the city will open a new space for people to recover and receive treatment for nearly 24 hours after they have overdosed on fentanyl or other drugs

Grammy-nominated musician Jelly Roll delivered an impassioned testimony before senate as lawmakers push for new anti-fentanyl legislation.

The overdoses were concentrated downtown before spreading across the city.

Officials in Austin, Texas, are investigating an "outbreak" of drug overdoses with more than 50 suspected cases and at least four people dead.

California is partnering with a New Jersey-based pharmaceutical company to purchase a generic version of Narcan

ABC News’ Dr. Jen Ashton discusses how the number of emergency visits among children for prescription opioids had decreased for a decade but increased between 2019 and 2020.

A U.S. citizen has been arrested crossing back into the U.S. from Mexico after authorities found an estimated $130,000 of fentanyl hidden in the taxi they were riding in.

ABC News' "Start Here" spoke with U.S. Secretary of Health and Human Services Xavier Becerra about the start of Medicare drug price negotiations.

Publicis Groupe SA agreed Thursday to pay $350 million to settle claims it helped OxyContin maker Purdue Pharma fuel the opioids epidemic in the United States.

Oregon officials declared a 90-day state of emergency to address Portland’s fentanyl crisis as fatal synthetic opioid overdoses there have risen 533% since 2018.

A pharmaceutical company says their new experimental drug could be an alternative to opioid-based painkillers.

Advocates feel presidential candidates have not discussed substance use disorder much – when, they believe, it should be highlighted both during and beyond the primary.

America’s illicit drugs are being laced with one of the deadliest opioids ever created, killing in record numbers. ABC News' Bob Woodruff travels to uncover the epidemic of fentanyl poisoning.

The musical artist got candid about his own personal addiction story and former life as a drug dealer during an emotional testimony to a Senate committee.

Jason DeFord, known by his stage name Jelly Roll, gave an emotional opening statement Thursday on overdoses at a Senate hearing on fentanyl.

Singer Jelly Roll speaks at the Senate hearing on a fentanyl bill, saying 190 people in America die daily from a drug overdose.

Republican presidential candidate and former New Jersey Gov. Chris Christie outlined his national drug crisis plan earlier this week.

Dr. Francis Martinis and his wife Jessica both plead “not guilty” to their charges on Long Island.

Several Virginia elementary school students needed medical attention Tuesday after eating gummy bears from a bag that tested positive for fentanyl, authorities said.

A settlement with Purdue Pharma hung in the balance at the Supreme Court as victims of the opioid epidemic urged justices to approve a deal with the company's owners.

Justices will review a $6 billion bankruptcy settlement between Purdue Pharma, the maker of OxyContin, and the victims and communities ravaged by the opioid crisis.

As tens of thousands of Americans die each year from synthetic opioids, namely fentanyl, federal officials say the illicit narcotics trade remains a critical problem

The U.S. attorney for the District of Columbia announced that 11 additional suspects, out of 23 total in custody, have been arrested in connection with a fentanyl distribution conspiracy.

New details of a federal investigation into a "massive" fentanyl ring in D.C. and elsewhere were released Monday with 11 additional arrests -- out of 23 total

ABC News’ Selina Wang and Mick Mulroy talk about the meeting between President Joe Biden and Mexico’s president and what the leaders will discuss.

Pres. Biden and Pres. Xi will discuss the escalating opioid crisis while at the APEC Summit.

Senior government officials are concerned that Congress may not pass enough funding to secure the border, as federal authorities work to stop illegal narcotics smuggling.

ABC News Chief Medical Correspondent Dr. Jen Ashton talks about a new study that discovered that limiting the use of opioids after surgery does not impact patient outcomes.

Two of the three suspects arrested in the death of a 1-year-old boy from fentanyl exposure at a Bronx, New York, day care center pleaded not guilty Thursday.

The machine-printed banners were purportedly signed by a faction of the Sinaloa cartel led by the sons of jailed Mexican drug lord Joaquin "El Chapo" Guzman.

NYC’s Health Commissioner Ashwin Vasan has advised residents to carry lifesaving Narcan and know how to use it as fentanyl deaths are on the rise.

Felix Herrera Garcia, the husband of the owner of the Bronx day care where a 1-year-old died of suspected fentanyl poisoning, returned Thursday to the United States.

The apartment was just six blocks from the day care where a 1-year-old died, and three other children had to be revived with Narcan after exposure to fentanyl, authorities said.

The overdose crisis reaches historic levels in New York City, according to new data from the city's Department of Health and Mental Hygiene.

Police say the drugs and weapons were discovered in a room across the hall from where a 10-year-old slept.

A kilogram of fentanyl was stored on top of children’s play mats used for napping at the New York City day care where a one-year-old boy died from exposure to the drug, a criminal complaint stated.

Two people in custody over the death of a 1-year old boy at a New York City day care are facing federal charges.

DHS looks to combat illicit drugs inside and out of the United States through targeted strategy

A 1-year-old boy has died and three other children were hospitalized after apparently coming into contact with an opioid at a day care center, according to the NYPD.

Illegal drugs are expected to be one of the biggest threats to national security in 2024, according to the Department of Homeland Security's annual threat study.

The percentage of overdose deaths from fentanyl combined with stimulants increased 50-fold between 2010 and 2021, according to a new analysis done by researchers.

ABC News’ Mireya Villarreal gets an inside look at “Operation Artemis” as federal authorities scour packages coming into Los Angeles International Airport for signs of the deadly drug.

From cost, accessibility, and how to find it, Dr. Jen Ashton breaks down what you need to know about Narcan coming to stores across the country.

The manufacturer of the overdose reversal drug Narcan said it will be available to buy over-the-counter starting in September.

The Supreme Court on Thursday temporarily blocked Purdue Pharma’s plan to emerge from bankruptcy that shielded the Sackler families from liability in the opioid epidemic

Xylazine, known on the street as tranq, is a cheap and powerful sedative, often used as a horse tranquilizer and is at the center of overdose deaths.

A recent study by the Centers for Disease Control and Prevention showed that nearly 80% of cocaine-related overdose deaths also involved opioids.

ABC News chief medical correspondent Dr. Jen Ashton explains a new study that found opioids not to be helpful in reducing pain severity or physical function for acute neck pain or back pain.

The California Highway Patrol has seized enough fentanyl in San Francisco in the past six weeks to kill the city's entire population nearly three times over.