ABC News correspondent Patrick Reevell has the latest from the war in the Middle East.

The head of MI5 says Britain is facing a staggering rise in attempts at assassination, sabotage and other crimes backed by Russia and Iran

Iran’s supreme leader has praised the country’s recent missile strike on Israel and said it is ready to do it again if necessary

ABC News’ Matt Gutman reports on the growing concerns of wider escalation in the Middle East.

Iranian state media says at least 26 people have died after drinking alcoholic beverages that contained toxic methanol

ABC News’ panels take a look at Wednesday’s biggest headlines.

U.S. officials are hoping Israel's response is "measured" and won't instigate further escalation.

India’s Mohun Bagan Super Giants has refused to travel to Iran to play Tractor SC in an Asian Champions League Two match scheduled for Wednesday because of the escalating security problems in the country and region

There are fears of a wider regional conflict as the U.S. has been working to de-escalate the heightened tensions in the Middle East.

Ofir Akunis, the Consul General of Israel in New York, said Israel’s response to missile attacks “will be very painful for Iran.”

Israel says it is preparing a counterstrike after the massive Iranian missile assault on Tuesday.

ABC News’ Ian Pannell and Martha Raddatz offer analysis following the major escalation from Iran.

ABC News’ Linsey Davis speaks with Sen. Katie Britt (R-AL) to discuss the developing situation in the Middle East and what’s ahead as VP candidates Tim Walz and JD Vance take the debate stage.

The crisis in the Middle East dominates the presidential campaign, as VP hopefuls Ohio Sen. JD Vance and Minnesota Gov. Tim Walz prepare for their one and only debate.

Iran launched missiles into Israel as retaliation for Israeli assassinations. The U.S. launched missiles to assist Israel in defending against the attack, an official said.

Israel is vowing to retaliate after Iran launched its biggest missile attack ever on Israel, targeting multiple air bases and intelligence headquarters.

Vice President Kamala Harris said she condemns the Iranian missile attack on Israel "unequivocally."

Aaron David Miller of the Carnegie Endowment and Alex Vatanka of the Middle East Institute join the show.

President Joe Biden addresses the crisis in the Middle East as Israel will have "significant response" after Iran's attack.

Oil prices climbed more than 3% on Tuesday.

The United States military coordinated closely with the Israeli Defense Forces to help defend Israel against the Iranian missile attack national security adviser Jake Sullivan told reporters.

The price of crude oil increased by more than 3% on Tuesday after rockets were fired into Israel.

ABC News’ Mary Bruce on White House reaction to Iran’s firing of missiles at Israel.

The Islamic Revolutionary Guard Corps said the missile attack was a retaliation for different assassinations carried out by Israel, Mehr News Agency reported.

A senior White House official told ABC News on Tuesday that the U.S. "has indications that Iran is preparing to imminently launch a ballistic missile attack against Israel."

The Justice Department unsealed an indictment Friday charging three Iranians over their alleged involvement in the hack of emails from former President Donald Trump's campaign.

Former President Donald Trump aimed his ire at Iran at a rally Wednesday following warnings from U.S. security officials that the country is targeting him.

They can "quickly and convincingly tailor synthetic content," an official said.

Federal authorities say Iranian hackers sent stolen Trump campaign material to individuals associated with the Biden campaign.

Kamala Harris’ campaign said it did not use materials that the FBI said Iranian hackers gathered from email accounts associated with Donald Trump’s campaign.

Intelligence agencies have assessed Russia, China and Iran are the biggest peddlers of influence operations in 2024.

U.S. intelligence agencies accuse Iranian hackers of stealing “non-public material from former President Trump’s campaign” and sending it to “individuals ... associated with President Biden’s campaign."

A retaliation "is definitive and will be measured and calculated," Iran's foreign minister said. The U.S. noted that two aircraft carrier strike groups will remain in the region to defend Israel.

The group, APT42, is associated with the Islamic Revolutionary Guard Corps (IRGC) according to Google.

ABC News' Linsey Davis speaks with retired Lt. Gen. Douglas Lute on the possibility of a widening conflict in the Middle East as the U.S. moves military assets to the region.

U.S. officials say announcing its military moves in the region is a message to Iran.

Antony Blinken told his G7 counterparts on Sunday that a response from Iran and Hezbollah could begin in the next 24 to 48 hours, according to two officials familiar.

The U.S. has sent additional ships and fighter jets to the region in support of Israel as Americans are warned to leave neighboring Lebanon to ensure their safety.

White House Deputy National Security Adviser Jon Finer said the U.S. is "preparing for every possibility" regarding potential Iran retaliation.

George Stephanopoulos interviews White House deputy national security adviser Jon Finer on “This Week.”

The U.S. has deployed ships and fighter jets to the region and issued a warning to Americans in Lebanon, ahead of an expected strike on Israel by Iran for the assassination of a top Hamas leader.

An expert said that the Israeli assassination of a Hamas leader could mean all-out war in the Middle East or lead to a quick resolution of the conflict in Gaza.

Ismail Haniyeh, the political leader of Hamas, has been killed in Tehran along with his bodyguard, Iran’s Islamic Revolutionary Guard Corps said in a statement.

Leaders across the Middle East voiced concerns after Israel claimed responsibility for the strike killing a top Hezbollah leader in Lebanon.

National security expert Morgan Ortagus explains how this could influence Trump's approach to Iran.

The U.S. Secret Service in recent weeks had increased Donald Trump's security detail due to intelligence Iran threated to assassinate him, according to three officials.

Iranian government actors seeking to "take advantage" of pro-Palestine protests, including funding some: DNI

Polls opened Friday in Iran for the run-off presidential election as none of the four candidates won more than 50% of the votes in the first round on June 28.

Officials say to expect a series of U.S. strikes against multiple targets.

Iran’s President Ebrahim Raisi passed away in a helicopter crash on May 19, 2024.