Tuesday, Sept. 22 at 4 p.m.

Arrival from Cuba

Location: Joint Base Andrews

His arrival at Andrews Air Force Base marks the first time the pope will set foot on U.S. soil. He will be greeted by President Obama, First Lady Michelle Obama, Vice President Joe Biden and his wife Jill.

Wednesday, Sept. 23 at 9:15 a.m.

Welcoming ceremony

Location: The White House

Pope Francis will appear at an official welcoming ceremony on the White House South Lawn. He will meet with President Obama following the South Lawn appearance.

Vatican Pool/Getty Images

Wednesday, Sept. 23 at 11:00 a.m.

Papal parade

Location: The Ellipse

After leaving the White House, Pope Francis will travel in the "popemobile" along 15th Street, Constitution Avenue and 17th Street, NW. The parade will be free and open to the public on a first-come, first-served basis. Gates will be opening for the Ellipse and the National Mall at 4:00 a.m.

Wednesday, Sept. 23 at 11:30 a.m.

Meeting with U.S. bishops

Location: Cathedral of St. Matthew the Apostle

His Holiness will lead a midday prayer from the Liturgy of Hours, alongside Bishops from the United States at the Cathedral of St. Matthew the Apostle.

Wednesday, Sept. 23 at 4:15 p.m.

Holy Mass and canonization of Junipero Serra

Location: Basilica of the National Shrine of the Immaculate Conception

Approximately 25,000 people are expected to attend this mass and it will serve as a canonization for Franciscan missionary Junipero Serra, a Spanish-born Franciscan Friar known for starting nine Spanish missions in California in the 1700s.

George Rose/Getty Images

Thursday, Sept. 24 at 9:20 a.m.

U.S. Capitol

Location: U.S. Capitol

Pope Francis will address a joint meeting of Congress, making him the first pope in history to do so. Video screens will be set up on the West Front of the Capitol toward the National Mall so thousands can watch the speech from outside.

Thursday, Sept. 24 at 11:15 a.m.

Visit to the Charitable Center of St. Patrick Parish and meeting with the homeless

Location: St. Patrick in the City

The pontiff will make a brief visit to the oldest Catholic church in the nation’s capital. Following the visit to St. Patrick's Parish, Pope Francis will give a blessing to clients of the St. Maria Meals program of the Catholic Charities for the Archdiocese of Washington. The pope is expected to enjoy a meal of chicken, green beans, carrots and pasta salad with the charity’s homeless clients.

Thursday, Sept. 24 at 4:00 p.m.

Departure for New York

Location: Joint Base Andrews

Pope Francis heads to the Empire State from the same base where he landed on Tuesday.

Thursday, Sept. 24 at 5:00 p.m.

Arrival in New York

Location: John F. Kennedy International Airport

An hour later, Pope Francis arrives at JFK airport in New York City. The Diocese of Brooklyn picked five Catholic school students who will greet Pope Francis when he touches down.

Thursday, Sept. 24 at 6:45 p.m.

Evening prayer (Vespers)

Location: St. Patrick's Cathedral

The pope will lead the evening prayer at a Vespers service held in the St. Patrick’s Cathedral. The event is only open to clergy of St. Patrick’s Cathedral, but a live stream will be available. Pope Francis will be the fourth pontiff to have visited the renowned cathedral. The young students will give the pontiff a bouquet filled with a list of prayers and good works from Catholic school students from Brooklyn and Queens.

Spencer Platt/Getty Images

Friday, Sept. 25 at 8:30 a.m.

Address to the United Nations

Location: United Nations

The United Nations is used to having high-profile attendees but Pope Francis will be breaking the mold on Friday. He is expected to address the General Assembly on strategies to combat poverty and protect the environment. His visit coincides with the UN's 70th anniversary.

Friday, Sept. 25 at 11:30 a.m.

Multi-religious service at 9/11 Memorial

Location: 9/11 Memorial and Museum, World Trade Center

The pontiff will visit the 9/11 Memorial site in lower Manhattan. He will then meet with local representatives of the world religions inside the museum's Foundation Hall, as part of a multi-religious meeting for peace.

Justin Lane-Pool/Getty Images

Friday, Sept. 25 at 4:00 p.m.

Visit to Our Lady Queen of Angels School

Location: Our Lady Queen of Angels School

Pope Francis will then visit a third grade class at Our Lady Queen of Angels, an elementary school in East Harlem.

Friday, Sept. 25 at 5:00 p.m.

Papal procession

Location: Central Park West between 72nd and 60th streets

A trip to “The Big Apple” wouldn’t be complete without a stroll through Central Park, so Pope Francis will motorcade between 72nd and 60th streets. More than 93,000 people entered a lottery for a free pair of tickets to the processional, and 80,000 tickets were given out.

Friday, Sept. 25 at 6:00 p.m.

Holy Mass

Location: Madison Square Garden

The pope will hold Mass in the same famous arena that houses playoff games and sold-out concerts. Madison Square Garden can hold up to 20,000 people.

Saturday, Sept. 26 at 8:40 a.m.

Departure for Philadelphia

Location: John F. Kennedy International Airport

Pope will travel by closed car to a downtown heliport, to catch a helicopter to JFK.

Saturday, Sept. 26 at 9:30 a.m.

Arrival in Philadelphia

Location: Philadelphia International Airport

Philadelphia’s Archbishop Charles Chaput, Pennsylvania Gov. Tom Wolf and the mayor of Philly Michael Nutter will roll out the red carpet for the Catholic leader. Pope Francis will be the second pope to visit the city.

Saturday, Sept. 26 at 10:30 a.m.

Holy Mass

Location: Cathedral Basilica of Saints Peter and Paul

This Mass is closed to the public and tickets have been limited to 1,600 people. The cathedral is the mother church of the Archdiocese of Philadelphia and the largest Catholic church in the state.

John Greim/LightRocket via Getty Images

Saturday, Sept. 26 at 4:45 p.m.

Visit to Independence Mall

Location: Independence Mall

Standing in front of America’s birthplace, the pope will give a speech about immigration and religious freedom. Following his speech, Francis plans on touring Independence Hall, which is expected to include a stop at the Liberty Bell.

Saturday, Sept. 26 at 7:30 p.m.

Festival of families

Location: Benjamin Franklin Parkway

The Festival of Families is the closing ceremony for the World Meetings of Families conference. Actor Mark Wahlberg will be hosting the outdoor ceremony and performers include Aretha Franklin, Andrea Bocelli, and the Fray. The pope will watch the celebration, hear from six families from different continents and give a speech.

Sunday, Sept. 27 at 9:15 a.m.

Meeting with U.S. bishops

Location: St. Martin's Chapel, St. Charles Borromeo Seminary

St. Charles is where Pope Francis will sleep while he’s in Philly. The seminary prepares men for the priesthood and the diaconate.

Sunday, Sept. 27 at 11:00 a.m.

Visit to Curran-Fromhold Correctional Facility

Location: Curran-Fromhold Correctional Facility

Pope Francis will visit the city’s largest jail, where most of the inmates are serving a maximum of two years or awaiting trial. The pope will give a speech in the gymnasium and after he’ll individually greet some of the 100 prisoners.

Sunday, Sept. 27 at 4:00 p.m.

Holy Mass concluding the World Meeting of Families

Location: Benjamin Franklin Parkway, Philadelphia Museum of Art steps

Before the pope gives the Holy Mass, he’ll ride down the mile-long street in his “popemobile.” This open-air Mass is the main event and is expected to attract over a million people.

Victor J. Blue/Bloomberg via Getty Images

Sunday, Sept. 27 at 7:00 p.m.

Visit with organizers, volunteers and benefactors of the World Meeting of Families

Location: Philadelphia International Airport

Approximately 500 people will bid Pope Francis farewell as he heads back to the Vatican. Vice President Biden and his family will lead the ceremony before His Holiness boards his return flight.

Sunday, Sept. 27 at 8:00 p.m.

Departure for Rome

Location: Philadelphia International Airport

Arrivederci Pope Francis! The pope will hold an on-board press conference before taking off. His plane is slated to touch down on Monday.