Lopez, who has been through a few divorces over the years herself, said, "I'm sad for them." She added, "They're both really lovely people, and just like Marc and I, it's not what you want to happen. You fight and you try until you realize you can't anymore."
Lopez, who split from Marc Anthony last summer, said she hasn't spoken to Tom or Katie, but she has "thought about it a lot."
J-Lo first got word of the TomKat divorce when she was in South America, and she recalled being "stunned" by the news.
Lopez added that it's the children that often are affected the most by divorce - Tom and Katie's daughter Suri, and his two children with ex-wife Nicole Kidman, Connor and Isabella.
She explained, "You know, I just wish them, you know, peace in their decision. And really for Suri and their other children as well, because you become such a family, it's not just Suri, it's Connor and Isabella and everybody, you know, you all become a family. And when that breaks apart, nobody wins, everybody's heartbroken in some way. And I just wish them peace."