Nov 28, 2011 2:23pm

Scientists ID ‘Morning Person’ Gene

Napoleon Bonaparte, Margaret Thatcher, Leonardo da Vinci … history is full of  names of famous figures who accomplished historical feats on reportedly few hours of sleep.

Now, new research suggests they may have had a  certain genetic advantage.

Scientists at Germany’s Ludwig Maximalians University of Munich have found that one gene, called ABCC9, influences sleep duration and could explain why certain people seem able to operate on limited amounts of shut-eye. The researchers studied responses to a sleep survey from more than 4,000 Europeans in seven different countries and also scanned their genomes. They found that people who had two copies of a particular variant of the ABCC9 gene generally reported sleeping for shorter periods than those who had two copies of a different version of the gene.

The ABCC9 gene has been previously linked  to heart disease and diabetes. These latest findings on the genetic factor’s role in sleep duration add to a growing body of evidence suggesting a connection between sleep and cardiovascular health. A 2008 study found a connection between lack of sleep and a dangerous build-up of calcium in the arteries. Sleep apnea, a sleep disorder marked by abnormal pauses in breathing,  has also been associated with high blood pressure and heart attacks.

“Apparently, the relationships of sleep duration with other conditions, such as heart disease and diabetes, can be in part explained by an underlying common molecular mechanism,” study author Karla Allebrandt told the U.K.’s Daily Mail.

The scientists also found that the ABCC9 gene controls sleep duration in fruit flies, providing a clue to the gene’s evolutionary age,  Allebrandt said.

Scientists  are gradually learning more about the genetics behind sleep habits. In 2008, researchers found a gene associated with narcolepsy, a rare but devastating sleep disorder. A 2010 study identified genetic differences that make some people sleepier than others, even after they’ve had a full night’s rest. Dr. Mark Mahowald, medical director of the Minnesota Regional Sleep Disorders Center, told ABC News that there’s more to sleep habits than most people think.

“Our society has equated sleepiness with defects of character, like laziness and depression, but really, some people are generally sleepier during the day,” Mahowald said. “We have to accept the fact that sleep duration is genetically determined and not a sign of a defect.”

ABC News’ Mikaela Conley contributed to this report.

User Comments

I’m shocked that Dr. Mark Mahowald says depression is “a defect of character.” That’s an extremely ignorant statement.

Posted by: Elizabeth Baker | November 28, 2011 November 28, 2011, 6:40 pm

Gattica here we come.

Posted by: Red | November 28, 2011 November 28, 2011, 8:14 pm

All I ask is that people who possess this gene and who are insanely alert and perky when even roosters are still sleeping be identified and segregated from those of us who feel half past dead until it’s mid-morning or later and we have some caffeine in our systems. Please.

Posted by: the catwhisperer | November 29, 2011 November 29, 2011, 1:24 am

“I’m shocked that Dr. Mark Mahowald says depression is ‘a defect of character.’ That’s an extremely ignorant statement.”

It’s more ignorant to read just his first few words and totally ignore the rest of the paragraph.
His conclusion is exactly the opposite of what you claim.

Go back and read it again — or better still, get someone to read it for you.

Posted by: Garfey Busby | November 29, 2011 November 29, 2011, 6:26 am

Dr. Mahowald says no such thing. Go back and read the whole paragraph, instead of taking his words out of context.

Posted by: Garfey Busby | November 29, 2011 November 29, 2011, 6:34 am

Catwhisperer: Post of the year award.

Posted by: jesuguru | November 29, 2011 November 29, 2011, 7:11 am

Maybe you two should re-read it. Actually, he did call depression a defect of character. What he refutes is the notion that defects of character cause sleepiness. He says rather, sleepyness is caused by genes. But that still leaves depression as a “defect of character.”

Posted by: AddyJ | November 29, 2011 November 29, 2011, 7:47 am

I always suspected morning people had some sort of genetic defect.

Posted by: Arf40 | November 29, 2011 November 29, 2011, 8:57 am

What is this, a Michael Crichton novel?

Posted by: JJ | November 29, 2011 November 29, 2011, 12:43 pm

Furthermore, why group “laziness” and “depression” together?? I, too, was shocked at Dr. Mahowald’s comment.

Aside from the final paragraph, I am overjoyed to see there are studies like this being done.

Posted by: LoveKitties | November 30, 2011 November 30, 2011, 3:51 am

There’s nothing wrong with grouping laziness and depression together. It’s like grouping genocide and cancer together as causes of death. Are they the same? Of course not but it doesn’t mean they can’t be grouped together as causes of death.

Posted by: Cory | December 4, 2011 December 4, 2011, 3:35 am

I’m hoping that the author of this article simply misquoted Dr. Mahowald. Characterizing depression as a defect of character is reprehensible.

“Catwhisperer” and Garfey Busby, you should learn to read for comprehension. Your ignorance is appalling. “Lovekitties”, are you attempting to justify the statement that depression is a defect of character? Is that what you believe? Mental illness is not, has never been, and never will be a defect of character.

Posted by: Ghod Dhammit | December 6, 2011 December 6, 2011, 12:09 pm

Leave a Reply

Do you have more information about this topic? If so, please click here to contact the editors of ABC News.