Ann Romney's debut on Twitter couldn't have come at a more opportune time.

Ann's first tweet came just moments after Democratic strategist and DNC adviser Hilary Rosen lobbed an insult at Ann Romney, suggesting that the 64-year-old mother of five and grandmother of 16 had never held a job.

"Guess what, his wife has actually never worked a day in her life," said Rosen, who was being interviewed by CNN's Anderson Cooper about the "war on women."

And then, just like that, a familiar name popped up on Twitter: @AnnDRomney.

"I made a choice to stay home and raise five boys. Believe me, it was hard work," Ann tweeted.

The Romney campaign confirmed to ABC News that the account belongs to Ann Romney.

The tweet came just as husband Mitt wrapped up a second day of campaigning that all but entirely focused on the "war against women," packing events with female business leaders and accusing the Obama administration's economic policies of hurting women.

"I could not disagree with Hilary Rosen any more strongly. Her comments were wrong and family should be off limits. She should apologize," Obama campaign manager Jim Messina said in a tweet.