Sunday on "This Week with George Stephanopoulos," former deputy chief of staff and senior adviser to President George W. Bush, Karl Rove, now a Fox News Contributor, faces off with Bloomberg TV contributor and former Obama White House senior adviser David Plouffe on the powerhouse roundtable.

With calls for Attorney General Eric Holder's resignation, how will the White House respond? Will the fallout from the IRS scandal affect President Obama's domestic agenda? How will Rep. Michele Bachmann's decision not to seek a fifth term impact the future of the Tea Party?

The two former advisers debate those issues and more with editor-in-chief of The Huffington Post Media Group Arianna Huffington, PBS' "Washington Week" moderator and managing editor Gwen Ifill and Wall Street Journal editorial page editor Paul Gigot Sunday on the "This Week" powerhouse roundtable.

And as the Syrian civil war continues, ABC News global affairs anchor Christiane Amanpour, TIME International editor Bobby Ghosh and Aaron David Miller, vice president of new initiatives at the Wilson Center, weigh in on what's next.

Then, in this week's "Sunday Spotlight," Rep. John Dingell, D-Mich., discusses his historic 57-year congressional career, as next week he becomes the longest-serving member of Congress.

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See the whole political picture, Sunday on "This Week."

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