On his hit TV show "Mad Men," Jon Hamm plays a dapper advertising exec from an era when a man could give a woman a piece of his mind.

So perhaps he did not take into account the power of 21 ^st century technology and 21 ^st century women who aren't afraid to fight back when he expressed his disgust with reality shows in an upcoming article in Elle UK magazine.

"Whether it's Paris Hilton or Kim Kardashian or whoever, stupidity is certainly celebrated. Being a f***ing idiot is a valuable commodity in this culture because you're rewarded significantly," Hamm, 41, says in the magazine's April issue. "It's celebrated. It doesn't make sense to me."

Those words were all it took for Kardashian to fire back on a tool not available in the 1960s world Hamm's TV show inhabits, Twitter.

"I respect Jon and I am a firm believer that everyone is entitled to their own opinion and that not everyone takes the same path in life," Kardashian, 31, tweeted on Monday.

"We're all working hard and we all have to respect one another. Calling someone who runs their own businesses, is a part of a successful TV show, produces, writes, designs, and creates, 'stupid,' is in my opinion careless," she wrote.

Kardashian is, of course, one leg in a multi-million dollar empire with her mom, Kris Jenner, and sisters Khloe and Kim, that has netted the family at least three reality shows on E!, a fashion line, a chain of high-end clothing stores and endorsements galore.

She was also, more infamously, the subject of a two-part reality special on E! in August documenting her wedding to NBA player Kris Humphries.  She filed for divorce from Humphries 72 days later.

That kind of attention has garnered Kardashian millions of dollars but also made her the subject of A-list scorn, with Hamm's comments just the latest example.

Last November, "James Bond" star Daniel Craig told UK GQ magazine, "Look at the Kardashians … you see that and you think, 'What, you mean all I have to do is behave like a … idiot on television and then you'll pay me millions?"

Oscar nominee Jonah Hill more recently called the family a "super disgusting" part of our culture, while his fellow funny man Matthew Lillard singled out the Kardashians as "the worst" of what he described as 100 percent atrocious reality TV.

While Kardashian tweets, another part of her family's reality empire, younger brother, Rob Kardashian, is speaking out to defend his limelight-loving clan.

"At the end of the day we do what we do and people are gonna hate no matter what," the former "Dancing With the Stars" contestant said Monday to TMZ about Hamm's comments.