Rubio will depart on his first foreign trip to visit countries in Central America that may be vital for carrying out the Trump administration's mass deportation plans.

After taking the oath of office, Marco Rubio promised that every action taken by the State Department will be determined by the answers to three questions.

After taking the oath of office, Marco Rubio promised that every action taken by the State Department will be determined by the answers to three questions.

The Senate voted unanimously to confirm Sen. Marco Rubio's as secretary of state on Monday, making him the first member of President Donald Trump's second Cabinet.

The newly-confirmed Secretary of State talks about becoming the first Latino to occupy the job, plans for the TikTok ban and President Donald Trump’s pardon of Jan. 6 defendants.

Rubio becomes the first member of Trump’s cabinet to be confirmed by the Senate.

Sen. Marco Rubio delivers his opening remarks before the Senate Foreign Relations Committee amid protests at his confirmation hearing for secretary of state.

Florida Sen. Marco Rubio is promising to implement President-elect Donald Trump’s “America First” vision as secretary of state

President-elect Trump plans to nominate GOP Sen. Marco Rubio of Florida for secretary of state, according to sources.

Rubio, 53, has served in the Senate since 2011. He is currently the vice-chair of the Senate Select Committee on Foreign Intelligence and also sits on the chamber's Committee on Foreign Relations.

ABC News’ Linsey Davis speaks with Sen. Marco Rubio (R-FL) about Trump’s immigration policies, J.D. Vance and the speculation surrounding President Joe Biden.

When Florida Sen. Marco Rubio was first elected to Congress, he was seen as a rising star in the GOP. Now, he’s being looked at as a possible VP Pick for Donald Trump.

The 12th Amendment states that presidential and vice presidential candidates running on the same ticket cannot reside in the same state.

ABC News’ Jonathan Karl interviews Sen. Marco Rubio, R-Fla., on “This Week.”

Marco Rubio said Monday that one of his campaign canvassers "was brutally attacked" in Hialeah, Florida, in what he described as a politically motivated assault

Sen. Rubio terminated Clint Reed "effective immediately" after he learned of "allegations of improper conduct."

The Republican senator visited the track on Tuesday.

Tillerson's nomination to be Secretary of State may face it's first roadblock.

Rubio keeps his seat in the U.S. Senate, defeating Rep. Patrick Murphy.

But the Florida senator did not rule out another presidential bid.

A report claims a Trump-owned company violated the U.S. trade embargo with Cuba.

Sen. Marco Rubio accused the TSA of lying about air marshals on Cuba flights.