Transcript for 'Nightline' co-anchor Juju Chang and team take the ALS pepper challenge
More than 17 million people dumping ice water on their heads, bringing massive attention to A.L.S., or Lou Gehrig's disease. Raising more than $220 million. Now another challenge is heating things up. Grabbing the attention of celebrities. Oh! Reporter: Hoping to once again raise money and awareness for the crippling disease. Oh, my god. Oh, my god. Reporter: The premise, just eat some hot peppers. Or donate money. And then challenge others to do the same. Lastly, I'm going to challenge juju Chang. Reporter: I was nominated by 23-year-old osi Mendoza, who we profiled last September while doing a story about the ice bucket challenge. It had been less than a year since his diagnosis. What was that like, getting that news? We never expected to hear that in our entire lives, to hear two to five years is the average years that someone lives after being diagnosed with A.L.S. Reporter: A.L.S. Has drastically affected life for the newlyweds, osiel and Bella. But he says he's determined to fight the disease. So to celebrate his 23rd birthday I stepped up to the plate and brought along my "Nightline" crew. All right, guys. Pick a pepper. The entire gang. Pick a pepper. Here we go. I accept your challenge. Here we go. Reporter: We then nominated my ABC colleague Michael Strahan and my friends at "Gma." Whoo! Reporter: Who took it up a notch, live. Yeah! Reporter: And if you decide to take the challenge for yourself, just watch out for the seeds. For the record, juju is the bravest and toughest of the "Nightline" three anchors.
This transcript has been automatically generated and may not be 100% accurate.