US Prepares for Hurricane Matthew, Evacuations Underway

Residents from the Carolinas to Florida are scrambling to evacuate or board up their homes and gather supplies to weather the storm.
1:59 | 10/06/16

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Transcript for US Prepares for Hurricane Matthew, Evacuations Underway
Right here in the U.S., we're following the millions of people evacuating as schools and businesses close along the coast. Rob Marciano is in Charleston, South Carolina. Good morning to you, rob. Reporter: Good morning, Amy, as you very well know, this part of South Carolina is called the low country. And for good reason. It's barely above sea level. Extremely vulnerable to hurricanes. That include this is city of Charleston, which, in the past 24 hours, has turned into a virtual ghost town. Millions fleeing their homes as hurricane Matthew barrels to the U.S. Food flying off shelves. Gas stations running out of fuel. I've spent almost an hour driving around looking for gas. Reporter: In South Carolina, interstate lanes reversed. Everyone has to go away from the coast. We want you to evacuate. We do not want you the stay. I gotta go home. Look at all the buses as far as the eye can see. Reporter: Buses offering free rides to those without cars. We decided to leave. Reporter: Hundreds hunkering down in shelters. I love my kids dearly. I want to do what's best for them. Reporter: Businesses letting out early so people can board up their own homes. Residents scrambling for supplies. Stacks of barren shelves at home improvement stores. Every chain saw in this Lowe's, sold out. People looking for generators. Reporter: They're some of millions concerned they'll be out power. How scare Rd people here? Freaking out, I think. Definitely chaotic. Reporter: I mean, people are nervous. It's been nearly 20 years since a big hurricane hit here. Floyd back in 1999. That took a two-hour drive to Columbia and made it a 12-hour nightmare. Big impacts tomorrow night and likely all day Saturday. Until then, anxious eyes on what this thing does to Florida first. Michael? Thank you, rob.

This transcript has been automatically generated and may not be 100% accurate.

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