Deadly tornado strikes the South

Students at Louisiana Tech raced to avoid a massive twister, with winds reaching speeds of at least 136 mph.
2:37 | 04/25/19

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Transcript for Deadly tornado strikes the South
Now, the violent storms and the trail of damage across more than 100 miles. Four confirmed tornadoes taking at least two lives. An ef-3 striking Ruston, Louisiana. The roof of this motel 6 completely gone. Staggering damage from an ef-2 in Bryan, Texas. And the line of storms now heading up the east coast, reaching the northeast tomorrow night. At this hour, tornado watches remain in place. ABC's Marcus Moore is in hard-hit Ruston, Louisiana. Reporter: Tonight, deadly tornadoes striking in the middle of the nights. Students at Louisiana tech racing to wake each other up. Oh, my gosh. Nick, get up! Reporter: Debris strewn across campus. The softball field in Tatters. Classes now cancelled. Ruston, Louisiana, taking a direct hit from a massive twister with at least 136-mile-per-hour winds. Ripping the roof off of this motel 6. I couldn't move out of my bed, basically. It was that terrifying. Reporter: Look at this. Stairs at this hotel that once led you to rooms, now you can see nothing but blue skies. Falling trees slicing the city's homes in half and claiming the lives of a mother and her son. Outside of Jackson, Mississippi, a tow truck driver involved in a two-vehicle crash on wet roads. His truck plunging off of a bridge. In New Orleans, severe thunderstorms swamping streets and delaying the start of the famed jazz and heritage festival. This tornado producing storm tracking across 150 miles, cutting a long swath of destruction. Buildings shredded in Bryan, Texas. Northeast of Austin Wednesday, this truck overturning, stuck in a flooded median. Good samaritans banding together, flipping that vehicle over and freeing the young driver trapped inside. And another look at the devastation. On the second floor of this hotel that took a direct hit, people in their rooms when this tornado came through in the middle of the night. To the east, tornado watches are in effect through the evening, Tom. This storm on the move. Incredible those guests survived that. Marcus, thank you. Let's get right over to rob Marciano here in New York, tracking it all. And rob, these storms are going to make major trouble for the whole east coast. Reporter: Yeah, it's not reaching up into the northeast, but the core right now is across the gulf coast. So, let's show you where the action is. Plowing through New Orleans and little buck si earlier today. Mobile, Pensacola. Now you are under a tornado watch. It will push through Atlanta overnight. The low strengthening across the Ohio valley. The mid-atlantic will get the vie veer threat tomorrow. By 7:00 P.M., Delaware, Philadelphia, D.C., and then getting ugly tomorrow night in New York, Connecticut and in through Boston and yet another quick-moving system set to impact this area over the weekend. Tom? All right, rob, thank you.

This transcript has been automatically generated and may not be 100% accurate.

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