Woman sentenced to 25 years for poisoning husband with eye drops

The family of Stephen Clayton speaks out after Lana Clayton pled guilty Thursday to poisoning and killing her husband with eye drops.
2:40 | 01/17/20

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Transcript for Woman sentenced to 25 years for poisoning husband with eye drops
We turn to the strange story of a woman who killed her husband by poisoning him with eye drops. She pled guilty Thursday sentenced to 25 years in prison. Now we're hearing from her husband's family. Diane Macedo spoke with them. Reporter: This morning a South Carolina woman is sentenced to over 20 years in prison after pleading guilty to killing her husband with eye drops. I am truly sorry. Reporter: Prosecutors say motivated by greed, nurse Lana Clayton secretly poisoned her husband by putting eye drops in his water for three days taking his computer and phone so he couldn't call for help. He laid there helpless Thursday and Friday waking up periodically from his misery thirsty, drinking more water. Reporter: Lana claimed her husband Steven Clayton was abusive and poisoned him only once hoping to punish not kill him. I did ultimately put the visine in his drink and I did it with the intent to make him sick and uncomfortable. Reporter: She expected the result to be like this scene from the movie "Wedding crashers" where Bradley cooper's crashing gets sick after drinking eye drops. Oh, no. Reporter: In an exclusive interview with ABC news Steven's sister says the reality was much darker. I think my brother was screaming for his life. Reporter: Steven Clayton was found dead July 2018 at the bottom of the stairs of his home. Police initially thought he had suffered a fatal fall or a heart attack but rosemary says Lana immediately started acting strangely. Financial record, papers, artwork, mementos, everything you can think of that she could throw into the fire pit, she threw into the fire pit including their bed. She threw their bed into the fire bit. She said the will seemingly vanished. He told you had a will. Your nephew saw the will and now the will is gone. That's right. And nobody know what is happened to it. After getting toxicology results officers called to the Clayton house reported finding several suicide notes, the house full of gas and Lana Clayton lying on her bed breathing but unconscious. After recovering in the hospital she was arrested in Steven's death. Whatever she thinks that my brother could done to cause her to want to make him ill, there's no excuse for taking somebody's Lana Clayton pleaded guilty to voluntary manslaughter and unlawful tampering with food. Of all the cases this one takes the cake for most bizarre, the judge said. It does. Coming up, that big super bowl news for demi Lovato.

This transcript has been automatically generated and may not be 100% accurate.

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