Jimmy Kimmel opens up about his new live shows in Brooklyn

The comedian sits down for an exclusive interview with ABC News' Amy Robach.
5:57 | 10/13/17

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Transcript for Jimmy Kimmel opens up about his new live shows in Brooklyn
We move on to our exclusive one-on-one with Jimmy Kimmel. I sat down with the late night host that talk about everything from his upcoming blockbuster show in Brooklyn to his headline making role in the health debate. I've been here for 25 years and make the pies this way. Reporter: Jimmy Kimmel and his show returning to Brooklyn. His birthblaise where he'll broadcast next week. What is it about Brooklyn. Brooklyn is a magical place. It really is. Every time I bring my kids there I feel guilty they don't get to run around the neighborhood with a bunch of other kids because we don't do that in L.A. We don't really know our neighbors until we're being deposed by them. So -- You have quite a few famous new yorkers coming on the show next week. Among them David Letterman. This is the first time he's done a late night show since his last show and that's terrifying for me. How hard or how long do you prepare the questions for David Letterman to come on your show. I feel like I've been preparing questions for Dave for my whole life. You have Billy Joel. Billy Joel is a favorite of mine. Howard Stern, Amy Schumer, Tracy Morgan, who is a good pal. We have a really good lineup. Announcer: Kimmel! Reporter: Jimmy has been making news not for jokes or skits but calling attention to the news of the day. My wife Molly gave birth to a boy, baby boy. Reporter: In a very personal way. You know, before 2014 if you were born with congenital heart deed like my son was, there was a good chance you'd never be able to get health insurance because you had a pre-existing condition. Reporter: In may he revealed his new son Billy was born with a heart defect and had to have emergency life-saving surgery. No parent should have to decide that. Reporter: Massive decisions with Billy. How is he? He's doing well. We're getting to have another operation. He's doing well. I love all the pictures of him smiling. He's very smiley and very cute. Was there a moment when you decided I'm now going to take something very personal and try to change the mood of not only America but our lawmakers. It's not something that I discussed with anyone other than my wife. But I did know that I had to say something. Thank you for listening. I promise I'm not going to cry for the rest of the show. Reporter: Long before that he lived through a health care and insurance struggle. I remember being fired from a radio job when I was 23 years old and I had to get my own health insurance paying $800 a month. I had no job so, you know, I've been there. I understand it and it's just kind of always stuck with me. Until something happens to you, I'm a cancer survivor and you actually realize what these costs are. You were very emotional when you talked about your son, also when you talked about the events in Las Vegas. Have you been surprised at the reaction. No, definitely not. It's embarrassing to me. I do my best to keep it together. I can't keep it in. You're a crier. Yes, I'm a crier. Even as a young boy I was a crier. It's a New York show next week. Any chance you could get president trump there. I would guess that he's not planning to visit me any time soon. I think he and Sean hannity have date flight on those nights so it's tough to break away. Wow like to have Donald Trump on the show? Absolutely. I have a lot of questions for Donald Trump. What would be your first one. I really -- maybe this is crazy but I feel like I could turn him around on a couple of things. Reporter: This after going toe-to-toe with Donald Trump Jr. He was calling you out along with other liberal Hollywood elite saying people are late in the game to talk about -- He's an idiot. Let's just start with that. This is an imbecile that is -- whose job seems to be tweeting as far as I can tell. But with that said, I do admire that he's very loyal to his father. First of all, the Harvey Weinstein thing, people like this false equivalence of that's somehow is equivalent to what happened in Las Vegas. I mean, Harvey Weinstein is not a person -- is not a friend of mine. I'm not in the movie business. And I'll add that that story came out like I think moments before we went to tape on Thursday and we didn't have a show on Friday so -- You addressed it on the following Monday. So, you know, of course, that was Dhar it's a convenientp -- now what they're doing now is they're trying to drag up any kind - especially these gun nuts trying to drag any -- like take any comedy bit I did out con tech and use it as some kind of proof. They're saying that I'm calling myself the moral conscience of America which I most certainly never did and most certainly never would. Brooklyn, New York. Reporter: You have surprises in store for people at home. We do. Some people will show up. We have some events that I think will be meaningful to tell people about and we hope it'll be a great week. And Kimmel told me he is going to continue to take on serious topics including health care. Overnight he tweeted about the health care news, trump ending Obamacare payments that subsidize insurance for millions of poor Americans saying, wait, he said I many agoing to take care of everybody. Everybody's going to be taken care of much better than they're taken care of now. Something trump said in an interview back in 2015 and also as I was interviewing Jimmy I noticed on his Twitter feed it says ready to serve. I asked him if he was serious. Could we see a president Kimmel. He said, believe me, nobody wants to see that. Most of all Jimmy. He knows has a platform. And has used it well. You can see "Jimmy Kimmel live" tonight on ABC and as you heard Jimmy Kimmel, live from Brooklyn, all next week and we cannot wait for that.

This transcript has been automatically generated and may not be 100% accurate.

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